(4-bromo-2,6-diisopropylphenyl)bis(2,4,6-triisopropylphenyl)phosphine

Base Information

• Chemical Name: (4-bromo-2,6-diisopropylphenyl)bis(2,4,6-triisopropylphenyl)phosphine
• CAS No.: 958007-24-4
• Molecular Formula: C₄₂H₆₂BrP
• Molecular Weight: 677.832
• Mol file: 958007-24-4.mol

Synonyms:(4-bromo-2,6-diisopropylphenyl)bis(2,4,6-triisopropylphenyl)phosphine

Chemical Property of (4-bromo-2,6-diisopropylphenyl)bis(2,4,6-triisopropylphenyl)phosphine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (4-bromo-2,6-diisopropylphenyl)bis(2,4,6-triisopropylphenyl)phosphine

There total 1 articles about (4-bromo-2,6-diisopropylphenyl)bis(2,4,6-triisopropylphenyl)phosphine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

5-bromo-2-iodo-1,3-diisopropylbenzene (946147-63-3) + bis(2,4,6-tri-isopropylphenyl)phosphinous chloride (182227-72-1) → (4-bromo-2,6-diisopropylphenyl)bis(2,4,6-triisopropylphenyl)phosphine (958007-24-4)

Guidance literature:

5-bromo-2-iodo-1,3-diisopropylbenzene; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 0.5h; Inert atmosphere;

With copper(l) chloride; In tetrahydrofuran; hexane; at -78 - 20 ℃; for 2.5h; Inert atmosphere;

bis(2,4,6-tri-isopropylphenyl)phosphinous chloride; In tetrahydrofuran; hexane; at -78 ℃; Reflux; Inert atmosphere;

DOI:10.1246/bcsj.80.1791

Reference yield: 98.0%

(4-bromo-2,6-diisopropylphenyl)bis(2,4,6-triisopropylphenyl)phosphine (958007-24-4) → (4-iodo-2,6-diisopropylphenyl)bis(2,4,6-triisopropylphenyl)phosphine

Guidance literature:

(4-bromo-2,6-diisopropylphenyl)bis(2,4,6-triisopropylphenyl)phosphine; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 0.5h; Inert atmosphere;

With iodine; In tetrahydrofuran; hexane; at -78 - 20 ℃; Inert atmosphere;

DOI:10.1016/j.tetlet.2019.151366

Reference yield: 74.0%

(4-bromo-2,6-diisopropylphenyl)bis(2,4,6-triisopropylphenyl)phosphine (958007-24-4) + N,N-dimethyl-formamide (68-12-2,33513-42-7) → (4-formyl-2,6-diisopropylphenyl)bis(2,4,6-triisopropylphenyl)phosphine (1335150-78-1)

Guidance literature:

(4-bromo-2,6-diisopropylphenyl)bis(2,4,6-triisopropylphenyl)phosphine; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 0.5h; Inert atmosphere;

N,N-dimethyl-formamide; In tetrahydrofuran; hexane; at 20 ℃; Inert atmosphere;

DOI:10.1016/j.jorganchem.2011.07.013

upstream raw materials:

5-bromo-2-iodo-1,3-diisopropylbenzene

bis(2,4,6-tri-isopropylphenyl)phosphinous chloride

Downstream raw materials:

bis[3,5-diisopropyl-4-bis(2,4,6-triisopropylphenyl)phosphinophenyl] nitroxide

(E)-4,4'-bis[bis(2,4,6-triisopropylphenyl)phosphino]-3,3',5,5'-tetraisopropylazobenzene

(4-azido-2,6-diisopropylphenyl)bis(2,4,6-triisopropylphenyl)phosphine

tert-butyl 3,5-diisopropyl-4-bis(2,4,6-triisopropylphenyl)phosphinophenyl nitroxide