4-bromo-3-tert-butoxycarbonylamino-5-(4-fluoro-benzyl)-pyridine-2-carboxylic acid isopropyl ester

Base Information

Chemical Name:4-bromo-3-tert-butoxycarbonylamino-5-(4-fluoro-benzyl)-pyridine-2-carboxylic acid isopropyl ester
CAS No.:1206528-84-8
Molecular Formula:C₂₁H₂₄BrFN₂O₄
Molecular Weight:467.335
Hs Code.:

Synonyms:4-bromo-3-tert-butoxycarbonylamino-5-(4-fluoro-benzyl)-pyridine-2-carboxylic acid isopropyl ester

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Chemical Property of 4-bromo-3-tert-butoxycarbonylamino-5-(4-fluoro-benzyl)-pyridine-2-carboxylic acid isopropyl ester

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Technology Process of 4-bromo-3-tert-butoxycarbonylamino-5-(4-fluoro-benzyl)-pyridine-2-carboxylic acid isopropyl ester

There total 1 articles about 4-bromo-3-tert-butoxycarbonylamino-5-(4-fluoro-benzyl)-pyridine-2-carboxylic acid isopropyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 1206528-83-7
C₂₆H₃₂BrFN₂O₆

: 1206528-84-8
4-bromo-3-tert-butoxycarbonylamino-5-(4-fluoro-benzyl)-pyridine-2-carboxylic acid isopropyl ester

Guidance literature:: With trifluoroacetic acid; In 1,2-dichloro-ethane; at 20 ℃;

Reference yield: 98.0%

: 1458-98-6
2-methyl-3-bromo-1-propene

: 1206528-84-8
4-bromo-3-tert-butoxycarbonylamino-5-(4-fluoro-benzyl)-pyridine-2-carboxylic acid isopropyl ester

: 1206529-86-3
C₂₅H₃₀BrFN₂O₄

Guidance literature:: With sodium hexamethyldisilazane; In tetrahydrofuran; N,N-dimethyl-formamide; at -10 - 20 ℃;

Reference yield: 72.0%

: 5460-29-7
2-(3-bromopropyl)isoindole-1,3-dione

: 1206528-84-8
4-bromo-3-tert-butoxycarbonylamino-5-(4-fluoro-benzyl)-pyridine-2-carboxylic acid isopropyl ester

: 1206528-95-1
C₃₂H₃₃BrFN₃O₆

Guidance literature:: 4-bromo-3-tert-butoxycarbonylamino-5-(4-fluoro-benzyl)-pyridine-2-carboxylic acid isopropyl ester; With sodium hexamethyldisilazane; In tetrahydrofuran; N,N-dimethyl-formamide; for 0.0833333h; Cooling with ice; Inert atmosphere;

2-(3-bromopropyl)isoindole-1,3-dione; In tetrahydrofuran; N,N-dimethyl-formamide; at 20 ℃; Inert atmosphere;