C₁₃H₁₈O₂Si

Base Information

• Chemical Name: C₁₃H₁₈O₂Si
• CAS No.: 1374575-88-8
• Molecular Formula: C₁₃H₁₈O₂Si
• Molecular Weight: 234.37
• Mol file: 1374575-88-8.mol

Synonyms:C₁₃H₁₈O₂Si

Chemical Property of C₁₃H₁₈O₂Si

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of C₁₃H₁₈O₂Si

There total 1 articles about C₁₃H₁₈O₂Si which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-hydroxy-5-methylbenzaldehyde (613-84-3) + trimethylsilylacetylene (1066-54-2) → C13H18O2Si (1374575-88-8)

Guidance literature:

trimethylsilylacetylene; With n-butyllithium; In tetrahydrofuran; at -78 - -40 ℃; Inert atmosphere;

2-hydroxy-5-methylbenzaldehyde; In tetrahydrofuran; at -78 ℃; for 4h; Inert atmosphere;

DOI:10.1055/s-0031-1290767

Reference yield:

C13H18O2Si (1374575-88-8) → C10H10O2 (1384475-76-6)

Guidance literature:

With tetrabutyl ammonium fluoride; In tetrahydrofuran; for 1h;

DOI:10.1055/s-0031-1290767

Reference yield:

C13H18O2Si (1374575-88-8) → ((5-methylbenzofuran-2-yl)methyl)diphenylphosphine oxide

Guidance literature:

Multi-step reaction with 2 steps

1: tetrabutyl ammonium fluoride / tetrahydrofuran / 0 °C / Inert atmosphere

2: tetrakis(actonitrile)copper(I) hexafluorophosphate / 1,2-dichloro-ethane / 4 h / 100 °C / Schlenk technique; Sealed tube; Inert atmosphere

With tetrakis(actonitrile)copper(I) hexafluorophosphate; tetrabutyl ammonium fluoride; In tetrahydrofuran; 1,2-dichloro-ethane;

DOI:10.1002/adsc.201701368

upstream raw materials:

2-hydroxy-5-methylbenzaldehyde

trimethylsilylacetylene

Downstream raw materials:

C₁₀H₁₀O₂