(4-{2-[(4-cyanophenyl)amino]-1-methylbenzimidazol-5-yloxy}-(2-pyridyl))-N-methylcarboxamide

Base Information

• Chemical Name: (4-{2-[(4-cyanophenyl)amino]-1-methylbenzimidazol-5-yloxy}-(2-pyridyl))-N-methylcarboxamide
• CAS No.: 611214-15-4
• Molecular Formula: C₂₂H₁₈N₆O₂
• Molecular Weight: 398.424
• Mol file: 611214-15-4.mol

Synonyms:(4-{2-[(4-cyanophenyl)amino]-1-methylbenzimidazol-5-yloxy}-(2-pyridyl))-N-methylcarboxamide

Chemical Property of (4-{2-[(4-cyanophenyl)amino]-1-methylbenzimidazol-5-yloxy}-(2-pyridyl))-N-methylcarboxamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (4-{2-[(4-cyanophenyl)amino]-1-methylbenzimidazol-5-yloxy}-(2-pyridyl))-N-methylcarboxamide

There total 2 articles about (4-{2-[(4-cyanophenyl)amino]-1-methylbenzimidazol-5-yloxy}-(2-pyridyl))-N-methylcarboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

4-(3-amino-4-methylamino-phenoxy)-pyridine-2-carboxylic acid methylamide (485841-47-2) + 4-isothiocyanatobenzonitrile (2719-32-6) → (4-{2-[(4-cyanophenyl)amino]-1-methylbenzimidazol-5-yloxy}-(2-pyridyl))-N-methylcarboxamide (611214-15-4)

Guidance literature:

With 2-chloro-1,3-dimethyl imidazolium chloride; N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20 ℃;

DOI:10.1016/j.tetlet.2010.07.177

Reference yield:

→ (4-{2-[(4-cyanophenyl)amino]-1-methylbenzimidazol-5-yloxy}-(2-pyridyl))-N-methylcarboxamide (611214-15-4)

Guidance literature:

upstream raw materials:

4-(3-amino-4-methylamino-phenoxy)-pyridine-2-carboxylic acid methylamide

4-isothiocyanatobenzonitrile