2-[4-(Dimethylamino)phenyl]propanoic acid

Base Information

Chemical Name:2-[4-(Dimethylamino)phenyl]propanoic acid
CAS No.:25899-90-5
Molecular Formula:C₁₁H₁₅NO₂
Molecular Weight:193.246
Hs Code.:
DSSTox Substance ID:DTXSID901258637

Synonyms:2-[4-(dimethylamino)phenyl]propanoic acid;25899-90-5;SCHEMBL472280;DTXSID901258637;AKOS010488638;2-[4-(dimethylamino)phenyl]propanoicacid;CS-0265527;EN300-99096;4-(Dimethylamino)-alpha-methylbenzeneacetic acid;Z792363902

Suppliers and Price of 2-[4-(Dimethylamino)phenyl]propanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 2-[4-(Dimethylamino)phenyl]propanoic acid

Chemical Property:

XLogP3:2.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:193.110278721
Heavy Atom Count:14
Complexity:196

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C1=CC=C(C=C1)N(C)C)C(=O)O

Technology Process of 2-[4-(Dimethylamino)phenyl]propanoic acid

There total 6 articles about 2-[4-(Dimethylamino)phenyl]propanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 2-(4-Dimethylamino-phenyl)-propionic acid (1S,2R,5S)-2-isopropyl-5-methyl-cyclohexyl ester

: 25899-90-5
2-<4-(dimethylamino)phenyl>propionic acid

Guidance literature:: With potassium hydroxide; water; In ethanol; for 24h; Heating;
DOI:10.1021/jm00037a022

Reference yield:

: 17078-28-3
2-[4-(dimethylamino)phenyl]acetic acid

: 25899-90-5
2-<4-(dimethylamino)phenyl>propionic acid

Guidance literature:: Multi-step reaction with 4 steps

1: SOCl₂ / 1 h / 60 °C

2: CH₂Cl₂ / 1 h / 40 °C

3: 1.) NaNH₂ / 1.) toluene, RT, 10 min, 2.) toluene, RT, 40 min

4: H₂O, ethan. KOH / ethanol / 24 h / Heating

With potassium hydroxide; thionyl chloride; water; sodium amide; In ethanol; dichloromethane;
DOI:10.1021/jm00037a022

Reference yield:

: 39889-72-0
2-(4-(dimethylamino)phenyl)acetyl chloride

: 25899-90-5
2-<4-(dimethylamino)phenyl>propionic acid

Guidance literature:: Multi-step reaction with 3 steps

1: CH₂Cl₂ / 1 h / 40 °C

2: 1.) NaNH₂ / 1.) toluene, RT, 10 min, 2.) toluene, RT, 40 min

3: H₂O, ethan. KOH / ethanol / 24 h / Heating

With potassium hydroxide; water; sodium amide; In ethanol; dichloromethane;
DOI:10.1021/jm00037a022