3-[(DIMETHYLAMINO)METHYL]-BENZENEACETIC ACID

Base Information

• Chemical Name: 3-[(DIMETHYLAMINO)METHYL]-BENZENEACETIC ACID
• CAS No.: 933737-02-1
• Molecular Formula: C₁₁H₁₅NO₂
• Molecular Weight: 193.246
• Mol file: 933737-02-1.mol

Synonyms:3-dimethylaminomethylphenylacetic acid

Chemical Property of 3-[(DIMETHYLAMINO)METHYL]-BENZENEACETIC ACID

Chemical Property:

Purity/Quality:

95%-98% ^*data from raw suppliers

3-(Dimethylaminomethyl)phenylaceticacidHCl 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-[(DIMETHYLAMINO)METHYL]-BENZENEACETIC ACID

There total 2 articles about 3-[(DIMETHYLAMINO)METHYL]-BENZENEACETIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(3-dimethylaminomethyl-phenyl)-acetic acid ethyl ester → 3-dimethylaminomethylphenylacetic acid (933737-02-1)

Guidance literature:

With hydrogenchloride; Heating;

DOI:10.1021/jm058220g

Reference yield:

ethyl 2-(3-formylphenyl)acetate (210115-24-5) → 3-dimethylaminomethylphenylacetic acid (933737-02-1)

Guidance literature:

Multi-step reaction with 2 steps

1: NaBH₄; Ti(i-PrO)4

2: aq. HCl / Heating

With titanium(IV) isopropylate; hydrogenchloride; sodium tetrahydroborate;

DOI:10.1021/jm058220g

Reference yield:

3-dimethylaminomethylphenylacetic acid (933737-02-1) → [2-(3-dimethylaminomethyl-phenyl)-1-hydroxy-1-phosphono-ethyl]-phosphonic acid

Guidance literature:

With phosphonic Acid; trichlorophosphate; In toluene; at 80 ℃; for 5h;

DOI:10.1021/jm058220g

upstream raw materials:

ethyl 2-(3-formylphenyl)acetate

Refernces