2-{4'-(11-methacryloyloxy-1-undecyloxy)biphenyl-4-yl}-5-(4-N,N-dimethylaminophenyl)-1,3,4-oxadiazole

Base Information

• Chemical Name: 2-{4'-(11-methacryloyloxy-1-undecyloxy)biphenyl-4-yl}-5-(4-N,N-dimethylaminophenyl)-1,3,4-oxadiazole
• CAS No.: 540473-60-7
• Molecular Formula: C₃₇H₄₅N₃O₄
• Molecular Weight: 595.782
• Mol file: 540473-60-7.mol

Synonyms:2-{4'-(11-methacryloyloxy-1-undecyloxy)biphenyl-4-yl}-5-(4-N,N-dimethylaminophenyl)-1,3,4-oxadiazole

Chemical Property of 2-{4'-(11-methacryloyloxy-1-undecyloxy)biphenyl-4-yl}-5-(4-N,N-dimethylaminophenyl)-1,3,4-oxadiazole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-{4'-(11-methacryloyloxy-1-undecyloxy)biphenyl-4-yl}-5-(4-N,N-dimethylaminophenyl)-1,3,4-oxadiazole

There total 6 articles about 2-{4'-(11-methacryloyloxy-1-undecyloxy)biphenyl-4-yl}-5-(4-N,N-dimethylaminophenyl)-1,3,4-oxadiazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

5-(4-(N,N-dimethylamino)phenyl)-1H-tetrazole (51449-84-4) + 2-methyl-acrylic acid 11-(4'-chlorocarbonyl-biphenyl-4-yloxy)-undecyl ester → 2-{4'-(11-methacryloyloxy-1-undecyloxy)biphenyl-4-yl}-5-(4-N,N-dimethylaminophenyl)-1,3,4-oxadiazole (540473-60-7)

Guidance literature:

With pyridine; at 135 ℃;

DOI:10.1021/ma021406u

Reference yield:

1-Bromo-11-hydroxyundecane (1611-56-9) → 2-{4'-(11-methacryloyloxy-1-undecyloxy)biphenyl-4-yl}-5-(4-N,N-dimethylaminophenyl)-1,3,4-oxadiazole (540473-60-7)

Guidance literature:

Multi-step reaction with 4 steps

1: 40 percent / potassium hydroxide; potassium iodide / methanol; H₂O / 24 h

2: 35 percent / hydroquinone; 4-toluenesulphonic acid monohydrate / benzene / 24 h / Heating

3: thionyl chloride / 2 h / 60 °C

4: 58 percent / pyridine / 135 °C

With pyridine; potassium hydroxide; thionyl chloride; p-toluenesulfonic acid monohydrate; hydroquinone; potassium iodide; In methanol; water; benzene;

DOI:10.1021/ma021406u

Reference yield:

4'-Hydroxybiphenyl-4-carboxylic acid (58574-03-1) → 2-{4'-(11-methacryloyloxy-1-undecyloxy)biphenyl-4-yl}-5-(4-N,N-dimethylaminophenyl)-1,3,4-oxadiazole (540473-60-7)

Guidance literature:

Multi-step reaction with 4 steps

1: 40 percent / potassium hydroxide; potassium iodide / methanol; H₂O / 24 h

2: 35 percent / hydroquinone; 4-toluenesulphonic acid monohydrate / benzene / 24 h / Heating

3: thionyl chloride / 2 h / 60 °C

4: 58 percent / pyridine / 135 °C

With pyridine; potassium hydroxide; thionyl chloride; p-toluenesulfonic acid monohydrate; hydroquinone; potassium iodide; In methanol; water; benzene;

DOI:10.1021/ma021406u

upstream raw materials:

5-(4-(N,N-dimethylamino)phenyl)-1H-tetrazole

1-Bromo-11-hydroxyundecane

4'-Hydroxybiphenyl-4-carboxylic acid

4'-(11-hydroxyundecyloxy)biphenyl-4-carboxylic acid