tert-butyl 2-(4-(2-chloro-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-ylamino)phenyl)acetate

Base Information

Chemical Name:tert-butyl 2-(4-(2-chloro-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-ylamino)phenyl)acetate
CAS No.:1621294-35-6
Molecular Formula:C₁₉H₂₂ClN₃O₂
Molecular Weight:359.856
Hs Code.:

Synonyms:tert-butyl 2-(4-(2-chloro-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-ylamino)phenyl)acetate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of tert-butyl 2-(4-(2-chloro-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-ylamino)phenyl)acetate

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Technology Process of tert-butyl 2-(4-(2-chloro-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-ylamino)phenyl)acetate

There total 1 articles about tert-butyl 2-(4-(2-chloro-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-ylamino)phenyl)acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 39.0%

: 5466-43-3
2,4-dichloro-6,7-dihydro-5H-cyclopentapyrimidine

: 174579-31-8
(4-aminophenyl)acetic acid tert-butyl ester

: 1621294-35-6
tert-butyl 2-(4-(2-chloro-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-ylamino)phenyl)acetate

Guidance literature:: In 1-methyl-pyrrolidin-2-one; at 80 ℃; Reagent/catalyst;

Reference yield: 75.0%

: 24424-99-5
di-tert-butyl dicarbonate

: 1621294-35-6
tert-butyl 2-(4-(2-chloro-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-ylamino)phenyl)acetate

: 1621294-37-8
tert-butyl 2-(4-(tert-butoxycarbonyl(2-chloro-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)amino)phenyl)acetate

Guidance literature:: With dmap; In tetrahydrofuran; at 20 ℃; for 6h;

Reference yield:

: 1621294-35-6
tert-butyl 2-(4-(2-chloro-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-ylamino)phenyl)acetate

: 98-80-6
phenylboronic acid

: 1436866-26-0
2-[4-[(2-phenyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)amino]phenyl]acetic acid

Guidance literature:: With tetrakis(triphenylphosphine) palladium⁽⁰⁾; caesium carbonate; In water; acetonitrile; at 125 ℃; for 0.5h; Microwave irradiation;