Technology Process of methyl 2,3-di-O-benzyl-α-D-glucopyranosiduronic acid
There total 5 articles about methyl 2,3-di-O-benzyl-α-D-glucopyranosiduronic acid which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
methyl 2,3-di-O-benzyl-α-D-glucopyranoside;
With
2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; [bis(acetoxy)iodo]benzene;
In
tetrahydrofuran;
at 0 - 20 ℃;
for 7h;
With
sodium chlorite; sodium dihydrogenphosphate; 2-Methyl-1-butene;
In
tetrahydrofuran; water; tert-butyl alcohol;
at 0 ℃;
for 1h;
DOI:10.1021/acs.orglett.7b00747
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: camphor-10-sulfonic acid / N,N-dimethyl-formamide / 18 h / 20 °C / pH 3 / Inert atmosphere
2.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0.17 h / 20 °C
2.2: 1.5 h / 20 °C
3.1: trifluoroacetic acid / water / 21 h / 20 °C
4.1: 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; [bis(acetoxy)iodo]benzene / dichloromethane; water / 2 h / 20 °C
With
2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; [bis(acetoxy)iodo]benzene; camphor-10-sulfonic acid; sodium hydride; trifluoroacetic acid;
In
dichloromethane; water; N,N-dimethyl-formamide; mineral oil;
DOI:10.1039/c8ob02225a
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0.17 h / 20 °C
1.2: 1.5 h / 20 °C
2.1: trifluoroacetic acid / water / 21 h / 20 °C
3.1: 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; [bis(acetoxy)iodo]benzene / dichloromethane; water / 2 h / 20 °C
With
2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; [bis(acetoxy)iodo]benzene; sodium hydride; trifluoroacetic acid;
In
dichloromethane; water; N,N-dimethyl-formamide; mineral oil;
DOI:10.1039/c8ob02225a
