diethyl (4-bromophenyl){[(E)-2-chloro-2-ethyl-1-butylidene]amino}methylphosphonate

Base Information

• Chemical Name: diethyl (4-bromophenyl){[(E)-2-chloro-2-ethyl-1-butylidene]amino}methylphosphonate
• CAS No.: 699000-92-5
• Molecular Formula: C₁₇H₂₆BrClNO₃P
• Molecular Weight: 438.729
• Mol file: 699000-92-5.mol

Synonyms:diethyl (4-bromophenyl){[(E)-2-chloro-2-ethyl-1-butylidene]amino}methylphosphonate

Chemical Property of diethyl (4-bromophenyl){[(E)-2-chloro-2-ethyl-1-butylidene]amino}methylphosphonate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of diethyl (4-bromophenyl){[(E)-2-chloro-2-ethyl-1-butylidene]amino}methylphosphonate

There total 2 articles about diethyl (4-bromophenyl){[(E)-2-chloro-2-ethyl-1-butylidene]amino}methylphosphonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

diethyl (4-bromophenyl){[(E)-2-ethyl-1-butylidene]amino}methylphosphonate (699000-79-8) → diethyl (4-bromophenyl){[(E)-2-chloro-2-ethyl-1-butylidene]amino}methylphosphonate (699000-92-5)

Guidance literature:

With N-chloro-succinimide; In tetrachloromethane; for 1h; Heating;

DOI:10.1055/s-2004-815969

Reference yield:

[Amino-(4-bromo-phenyl)-methyl]-phosphonic acid diethyl ester (189180-13-0) → diethyl (4-bromophenyl){[(E)-2-chloro-2-ethyl-1-butylidene]amino}methylphosphonate (699000-92-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 98 percent / MgSO₄ / CH₂Cl₂ / 3 h / Heating

2: 98 percent / N-chlorosuccinimide / CCl₄ / 1 h / Heating

With N-chloro-succinimide; magnesium sulfate; In tetrachloromethane; dichloromethane;

DOI:10.1055/s-2004-815969

Reference yield:

diethyl (4-bromophenyl){[(E)-2-chloro-2-ethyl-1-butylidene]amino}methylphosphonate (699000-92-5) → diethyl (E)-(4-bromophenyl){[(Z)-2-ethylbut-1-enyl]imino}methylphosphonate (699001-04-2)

Guidance literature:

With sodium hydride; In tetrahydrofuran; at 20 ℃;

DOI:10.1055/s-2004-815969

upstream raw materials:

diethyl (4-bromophenyl){[(E)-2-ethyl-1-butylidene]amino}methylphosphonate

[Amino-(4-bromo-phenyl)-methyl]-phosphonic acid diethyl ester

Downstream raw materials:

diethyl (E)-(4-bromophenyl){[(Z)-2-ethylbut-1-enyl]imino}methylphosphonate