2-{1-[3-(4-Methoxy-benzyloxy)-phenyl]-3-trimethylsilanyl-prop-2-ynyl}-malonic acid diethyl ester

Base Information

Chemical Name:2-{1-[3-(4-Methoxy-benzyloxy)-phenyl]-3-trimethylsilanyl-prop-2-ynyl}-malonic acid diethyl ester
CAS No.:115062-57-2
Molecular Formula:C₂₇H₃₄O₆Si
Molecular Weight:482.649
Hs Code.:

Synonyms:2-{1-[3-(4-Methoxy-benzyloxy)-phenyl]-3-trimethylsilanyl-prop-2-ynyl}-malonic acid diethyl ester

Suppliers and Price of 2-{1-[3-(4-Methoxy-benzyloxy)-phenyl]-3-trimethylsilanyl-prop-2-ynyl}-malonic acid diethyl ester

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 2 raw suppliers

Chemical Property of 2-{1-[3-(4-Methoxy-benzyloxy)-phenyl]-3-trimethylsilanyl-prop-2-ynyl}-malonic acid diethyl ester

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of 2-{1-[3-(4-Methoxy-benzyloxy)-phenyl]-3-trimethylsilanyl-prop-2-ynyl}-malonic acid diethyl ester

There total 1 articles about 2-{1-[3-(4-Methoxy-benzyloxy)-phenyl]-3-trimethylsilanyl-prop-2-ynyl}-malonic acid diethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 47.0%

: 61210-52-4
(trimethylsilyl)ethynylmagnesium bromide

: 108781-15-3
3-(p-methoxybenzyloxy)benzylidenemalonic acid diethyl ester

: 115062-57-2
2-{1-[3-(4-Methoxy-benzyloxy)-phenyl]-3-trimethylsilanyl-prop-2-ynyl}-malonic acid diethyl ester

Guidance literature:: DOI:10.1021/jm00399a002

Reference yield:

: 115062-57-2
2-{1-[3-(4-Methoxy-benzyloxy)-phenyl]-3-trimethylsilanyl-prop-2-ynyl}-malonic acid diethyl ester

: 115062-66-3
{2-[3-(4-Methoxy-benzyloxy)-phenyl]-but-3-enyl}-carbamic acid 4-methoxy-benzyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) aq. NaOH, 2.) aq. pyridine / 1.) ethanol, reflux, 2.) 100 deg C

2: 50 percent / diphenyl phosphorazidate, Et₃N / toluene / 100 °C

3: hydrogen / Pd/Ba₂CO₃ / CH₂Cl₂

With pyridine; sodium hydroxide; diphenyl phosphoryl azide; hydrogen; triethylamine; palladium; In dichloromethane; toluene;
DOI:10.1021/jm00399a002

Reference yield:

: 115062-57-2
2-{1-[3-(4-Methoxy-benzyloxy)-phenyl]-3-trimethylsilanyl-prop-2-ynyl}-malonic acid diethyl ester

: 115062-63-0
{2-[3-(4-Methoxy-benzyloxy)-phenyl]-but-3-ynyl}-carbamic acid 4-methoxy-benzyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) aq. NaOH, 2.) aq. pyridine / 1.) ethanol, reflux, 2.) 100 deg C

2: 50 percent / diphenyl phosphorazidate, Et₃N / toluene / 100 °C

With pyridine; sodium hydroxide; diphenyl phosphoryl azide; triethylamine; In toluene;
DOI:10.1021/jm00399a002