methyl 5-(4-phenyl-1H-1,2,3-triazol-1-yl)pentanoate

Base Information

• Chemical Name: methyl 5-(4-phenyl-1H-1,2,3-triazol-1-yl)pentanoate
• CAS No.: 1037510-80-7
• Molecular Formula: C₁₄H₁₇N₃O₂
• Molecular Weight: 259.308
• Mol file: 1037510-80-7.mol

Synonyms:methyl 5-(4-phenyl-1H-1,2,3-triazol-1-yl)pentanoate

Chemical Property of methyl 5-(4-phenyl-1H-1,2,3-triazol-1-yl)pentanoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of methyl 5-(4-phenyl-1H-1,2,3-triazol-1-yl)pentanoate

There total 2 articles about methyl 5-(4-phenyl-1H-1,2,3-triazol-1-yl)pentanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

5-azidovaleric acid methyl ester (127811-93-2) + phenylacetylene (536-74-3) → methyl 5-(4-phenyl-1H-1,2,3-triazol-1-yl)pentanoate (1037510-80-7)

Guidance literature:

With copper(l) iodide; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; at 20 ℃; for 24h;

DOI:10.1016/j.bmc.2008.03.050

Reference yield:

5-azidovaleric acid methyl ester (127811-93-2) + benzyl azide (622-79-7) → methyl 5-(4-phenyl-1H-1,2,3-triazol-1-yl)pentanoate (1037510-80-7) + C14H17N3O2

Guidance literature:

With 25percentCu-doped zeolitic imidazolate framework ZIF-8; In toluene; at 100 ℃; for 3h; Reagent/catalyst; Overall yield = 97%; regioselective reaction;

DOI:10.1039/c4cy01505c

Reference yield: 50.0%

methyl 5-(4-phenyl-1H-1,2,3-triazol-1-yl)pentanoate (1037510-80-7) → C13H16N4O2 (1037510-91-0)

Guidance literature:

With potassium cyanide; hydroxylamine; In tetrahydrofuran; methanol; water; at 20 ℃; for 24h;

DOI:10.1016/j.bmc.2008.03.050

upstream raw materials:

5-azidovaleric acid methyl ester

phenylacetylene

benzyl azide

Downstream raw materials:

C₁₃H₁₆N₄O₂