C₉H₆BrClO

Base Information

• Chemical Name: C₉H₆BrClO
• CAS No.: 119411-68-6
• Molecular Formula: C₉H₆BrClO
• Molecular Weight: 245.503
• Mol file: 119411-68-6.mol

Synonyms:C₉H₆BrClO

Chemical Property of C₉H₆BrClO

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₉H₆BrClO

There total 2 articles about C₉H₆BrClO which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-bromocinnamic acid (7345-79-1,20595-39-5,7499-56-1) → C9H6BrClO (119411-68-6,851664-10-3)

Guidance literature:

With oxalyl dichloride; In dichloromethane; at 25 ℃;

DOI:10.3390/molecules14104166

Reference yield:

ortho-bromobenzaldehyde (6630-33-7) → C9H6BrClO (119411-68-6,851664-10-3)

Guidance literature:

Multi-step reaction with 2 steps

2: oxalyl dichloride / dichloromethane / 0 °C

With oxalyl dichloride; In dichloromethane; 1: Knoevenagel condensation;

DOI:10.1016/j.bmcl.2011.11.078

Reference yield: 87.0%

C9H6BrClO (119411-68-6,851664-10-3) + C15H12N2O → 8-bromo-4-phenyl-2-(pyridin-2-ylmethyl)-1H-benzo[f]isoindole-1,3(2H)-dione

Guidance literature:

C₁₅H₁₂N₂O; With sodium hydride; In tetrahydrofuran; mineral oil; at 0 ℃; for 0.5h;

C₉H₆BrClO; In tetrahydrofuran; mineral oil; at 0 - 20 ℃; for 3h;

DOI:10.1039/d1cc01437d

upstream raw materials:

2-bromocinnamic acid

ortho-bromobenzaldehyde

Downstream raw materials:

(E)-3-(2-bromophenyl)-N-[4-methyl-3-(4-pyridin-3-ylpyrimidin-2-ylamino)phenyl]acrylamide

C₁₆H₁₄BrNO

2-(2-bromophenyl)-5,6,7-trimethoxy-4H-chromen-4-one

2-(2-bromophenyl)-5-hydroxy-6,7-dimethoxy-4H-chromen-4-one

Refernces

• 1、 Chen, Xia,Zhong, Cheng,Lu, Yuling,Yao, Meng,Guan, Zhenhua,Chen, Chunmei,Zhu, Hucheng,Luo, Zengwei,Zhang, Yonghui. "Practical access to fluorescent 2,3-naphthalimide derivatives: Via didehydro-Diels-Alder reaction". supporting information. p. 5155 - 5158. Retrieved 2021/05/31.
• 2、 Zhou, Kun,Chen, Dongdong,Li, Bin,Zhang, Bingyu,Miao, Fang,Zhou, Le. "Bioactivity and structure-activity relationship of cinnamic acid esters and their derivatives as potential antifungal agents for plant protection". . . Retrieved 2017/04/26.