(2R,3S,4S,4aS,10bS)-9-(4-ethylbenzyl)-3,4-dihydroxy-2-(hydroxymethyl)-3,4,4a,10b-tetrahydropyrano[3,2-c][2]benzopyran-6(2H)-one

Base Information

Chemical Name:(2R,3S,4S,4aS,10bS)-9-(4-ethylbenzyl)-3,4-dihydroxy-2-(hydroxymethyl)-3,4,4a,10b-tetrahydropyrano[3,2-c][2]benzopyran-6(2H)-one
CAS No.:1428730-95-3
Molecular Formula:C₂₂H₂₄O₆
Molecular Weight:384.429
Hs Code.:

Synonyms:(2R,3S,4S,4aS,10bS)-9-(4-ethylbenzyl)-3,4-dihydroxy-2-(hydroxymethyl)-3,4,4a,10b-tetrahydropyrano[3,2-c][2]benzopyran-6(2H)-one

Suppliers and Price of (2R,3S,4S,4aS,10bS)-9-(4-ethylbenzyl)-3,4-dihydroxy-2-(hydroxymethyl)-3,4,4a,10b-tetrahydropyrano[3,2-c][2]benzopyran-6(2H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of (2R,3S,4S,4aS,10bS)-9-(4-ethylbenzyl)-3,4-dihydroxy-2-(hydroxymethyl)-3,4,4a,10b-tetrahydropyrano[3,2-c][2]benzopyran-6(2H)-one

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2R,3S,4S,4aS,10bS)-9-(4-ethylbenzyl)-3,4-dihydroxy-2-(hydroxymethyl)-3,4,4a,10b-tetrahydropyrano[3,2-c][2]benzopyran-6(2H)-one

There total 10 articles about (2R,3S,4S,4aS,10bS)-9-(4-ethylbenzyl)-3,4-dihydroxy-2-(hydroxymethyl)-3,4,4a,10b-tetrahydropyrano[3,2-c][2]benzopyran-6(2H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₅₀H₅₀O₇

: 1428730-95-3
(2R,3S,4S,4aS,10bS)-9-(4-ethylbenzyl)-3,4-dihydroxy-2-(hydroxymethyl)-3,4,4a,10b-tetrahydropyrano[3,2-c][2]benzopyran-6(2H)-one

Guidance literature:: With palladium 10% on activated carbon; hydrogen; In methanol; ethyl acetate; at 30 ℃; for 6h; under 2250.23 Torr; Inert atmosphere;

Reference yield:

: 1427370-39-5
2-bromo-4-(4-ethylbenzoyl)benzoic acid methyl ester

: 1428730-95-3
(2R,3S,4S,4aS,10bS)-9-(4-ethylbenzyl)-3,4-dihydroxy-2-(hydroxymethyl)-3,4,4a,10b-tetrahydropyrano[3,2-c][2]benzopyran-6(2H)-one

Guidance literature:: Multi-step reaction with 7 steps

1.1: trifluoroacetic acid; triethylsilane; trifluorormethanesulfonic acid / 2 h / 20 - 75 °C / Inert atmosphere

2.1: lithium aluminium tetrahydride / tetrahydrofuran / 3 h / 0 - 20 °C / Inert atmosphere

3.1: sodium hydride / N,N-dimethyl-formamide / 0.5 h / 0 °C / Inert atmosphere

3.2: 0 - 20 °C / Inert atmosphere

4.1: n-butyllithium / tetrahydrofuran; hexane / 0.33 h / -78 °C / Inert atmosphere

4.2: 2.5 h / -78 - -60 °C / Inert atmosphere

4.3: 2 h / -40 - -10 °C / Inert atmosphere

5.1: acetic acid; sodium acetate; palladium dichloride / water / 1 h / 20 - 70 °C

6.1: Jones reagent / acetone / 2 h / 0 - 20 °C

7.1: palladium 10% on activated carbon; hydrogen / ethyl acetate; methanol / 6 h / 30 °C / 2250.23 Torr / Inert atmosphere

With triethylsilane; lithium aluminium tetrahydride; Jones reagent; n-butyllithium; trifluorormethanesulfonic acid; palladium 10% on activated carbon; hydrogen; sodium acetate; sodium hydride; acetic acid; trifluoroacetic acid; palladium dichloride; In tetrahydrofuran; methanol; hexane; water; ethyl acetate; N,N-dimethyl-formamide; acetone;

Reference yield:

: 1427370-41-9
1-(allyloxymethyl)-2-bromo-4-(4-ethylbenzyl)benzene

: 1428730-95-3
(2R,3S,4S,4aS,10bS)-9-(4-ethylbenzyl)-3,4-dihydroxy-2-(hydroxymethyl)-3,4,4a,10b-tetrahydropyrano[3,2-c][2]benzopyran-6(2H)-one

Guidance literature:: Multi-step reaction with 4 steps

1.1: n-butyllithium / tetrahydrofuran; hexane / 0.33 h / -78 °C / Inert atmosphere

1.2: 2.5 h / -78 - -60 °C / Inert atmosphere

1.3: 2 h / -40 - -10 °C / Inert atmosphere

2.1: acetic acid; sodium acetate; palladium dichloride / water / 1 h / 20 - 70 °C

3.1: Jones reagent / acetone / 2 h / 0 - 20 °C

4.1: palladium 10% on activated carbon; hydrogen / ethyl acetate; methanol / 6 h / 30 °C / 2250.23 Torr / Inert atmosphere

With Jones reagent; n-butyllithium; palladium 10% on activated carbon; hydrogen; sodium acetate; acetic acid; palladium dichloride; In tetrahydrofuran; methanol; hexane; water; ethyl acetate; acetone;