1,3-bis(2',3',4',6'-tetra-O-benzoyl-α-D-mannopyranosyloxy)-2-(azidomethyl)propane

Base Information

• Chemical Name: 1,3-bis(2',3',4',6'-tetra-O-benzoyl-α-D-mannopyranosyloxy)-2-(azidomethyl)propane
• CAS No.: 882516-49-6
• Molecular Formula: C₇₂H₆₁N₃O₂₀
• Molecular Weight: 1288.28
• Mol file: 882516-49-6.mol

Synonyms:1,3-bis(2',3',4',6'-tetra-O-benzoyl-α-D-mannopyranosyloxy)-2-(azidomethyl)propane

Chemical Property of 1,3-bis(2',3',4',6'-tetra-O-benzoyl-α-D-mannopyranosyloxy)-2-(azidomethyl)propane

Chemical Property:

Purity/Quality:

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Technology Process of 1,3-bis(2',3',4',6'-tetra-O-benzoyl-α-D-mannopyranosyloxy)-2-(azidomethyl)propane

There total 1 articles about 1,3-bis(2',3',4',6'-tetra-O-benzoyl-α-D-mannopyranosyloxy)-2-(azidomethyl)propane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

5-azidomethyl-1,3-propanediol + 2,3,4,6-tetra-O-benzoyl-α-D-mannopyranosyl trichloroacetimidate (183901-63-5) → 1,3-bis(2',3',4',6'-tetra-O-benzoyl-α-D-mannopyranosyloxy)-2-(azidomethyl)propane (882516-49-6)

Guidance literature:

With trimethylsilyl trifluoromethanesulfonate; In dichloromethane; at 0 - 20 ℃; for 2h;

DOI:10.1002/ejoc.200500692

Reference yield: 56.0%

1,3-bis(2',3',4',6'-tetra-O-benzoyl-α-D-mannopyranosyloxy)-2-(azidomethyl)propane (882516-49-6) + carbon disulfide (75-15-0,12122-00-8) → 1,3-bis(2,3,4,6-tetra-O-benzoyl-α-D-mannopyranosyloxy)-2-(isothiocyanatomethyl)propane

Guidance literature:

With triethyl phosphite; In toluene; at 80 ℃; for 8h;

DOI:10.1002/ejoc.200500692

Reference yield:

1,3-bis(2',3',4',6'-tetra-O-benzoyl-α-D-mannopyranosyloxy)-2-(azidomethyl)propane (882516-49-6) → 1,3-bis(2',3',4',6'-tetra-O-benzoyl-α-D-mannopyranosyloxy)-2-(aminomethyl)propane

Guidance literature:

With triphenylphosphine; In tetrahydrofuran; at 0 - 20 ℃; for 1h;

DOI:10.1002/ejoc.200500692

upstream raw materials:

2,3,4,6-tetra-O-benzoyl-α-D-mannopyranosyl trichloroacetimidate