Technology Process of C38H49FN4O8S
There total 12 articles about C38H49FN4O8S which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
hydrogen;
palladium on activated charcoal;
In
ethanol;
at 25 ℃;
under 759.826 Torr;
- Guidance literature:
-
Multi-step reaction with 7 steps
1.1: boron tribromide / dichloromethane / 3 h / 0 °C
2.1: potassium carbonate / acetone / 20 °C
3.1: 2-hydroxypyridin; N-ethyl-N,N-diisopropylamine / dichloromethane / 20 h / 70 °C
4.1: polymer suported triphenylphosphine / tetrahydrofuran; methanol / 24 h
5.1: N-ethyl-N,N-diisopropylamine; HATU / N,N-dimethyl-formamide / 0.25 h / 0 °C
5.2: 8.17 h / 0 - 20 °C
6.1: Hoveyda-Grubbs catalyst second generation / 1,2-dichloro-ethane / 90 °C
7.1: hydrogen / palladium on activated charcoal / ethanol / 25 °C / 759.83 Torr
With
2-hydroxypyridin; hydrogen; boron tribromide; potassium carbonate; N-ethyl-N,N-diisopropylamine; HATU;
Hoveyda-Grubbs catalyst second generation; palladium on activated charcoal;
In
tetrahydrofuran; methanol; ethanol; dichloromethane; 1,2-dichloro-ethane; N,N-dimethyl-formamide; acetone;
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: potassium carbonate / acetone / 20 °C
2.1: 2-hydroxypyridin; N-ethyl-N,N-diisopropylamine / dichloromethane / 20 h / 70 °C
3.1: polymer suported triphenylphosphine / tetrahydrofuran; methanol / 24 h
4.1: N-ethyl-N,N-diisopropylamine; HATU / N,N-dimethyl-formamide / 0.25 h / 0 °C
4.2: 8.17 h / 0 - 20 °C
5.1: Hoveyda-Grubbs catalyst second generation / 1,2-dichloro-ethane / 90 °C
6.1: hydrogen / palladium on activated charcoal / ethanol / 25 °C / 759.83 Torr
With
2-hydroxypyridin; hydrogen; potassium carbonate; N-ethyl-N,N-diisopropylamine; HATU;
Hoveyda-Grubbs catalyst second generation; palladium on activated charcoal;
In
tetrahydrofuran; methanol; ethanol; dichloromethane; 1,2-dichloro-ethane; N,N-dimethyl-formamide; acetone;