Technology Process of N-(2-methyl-4-phenylbutyl)aniline
There total 3 articles about N-(2-methyl-4-phenylbutyl)aniline which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
C31H53N5Ti;
In
toluene;
at 140 ℃;
for 24h;
regioselective reaction;
Inert atmosphere;
Schlenk technique;
Glovebox;
DOI:10.1016/j.tet.2019.04.041
- Guidance literature:
-
4-Phenylbut-1-ene; N-Phenyl-N-<(trimethylsilyl)methyl>amine;
With
bis((3,5-bis(tert-butyldimethylsilyl)phenyl)(6-((3,5-bis(tert-butyldimethyl-silyl)phenyl)amino)pyridin-2-yl)amino)bis(dimethylamino)titanium;
In
toluene;
at 140 ℃;
for 24h;
Schlenk technique;
Autoclave;
Inert atmosphere;
Glovebox;
Sealed tube;
With
tetrabutyl ammonium fluoride;
at 110 ℃;
for 15h;
regioselective reaction;
Schlenk technique;
Inert atmosphere;
Glovebox;
DOI:10.1002/chem.202003223
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: n-butyllithium / hexane; tetrahydrofuran / 0.5 h / 0 °C / Inert atmosphere; Schlenk technique
1.2: 16 h / 80 °C / Inert atmosphere; Schlenk technique
2.1: bis((3,5-bis(tert-butyldimethylsilyl)phenyl)(6-((3,5-bis(tert-butyldimethyl-silyl)phenyl)amino)pyridin-2-yl)amino)bis(dimethylamino)titanium / toluene / 24 h / 140 °C / Schlenk technique; Autoclave; Inert atmosphere; Glovebox; Sealed tube
2.2: 15 h / 110 °C / Schlenk technique; Inert atmosphere; Glovebox
With
n-butyllithium; bis((3,5-bis(tert-butyldimethylsilyl)phenyl)(6-((3,5-bis(tert-butyldimethyl-silyl)phenyl)amino)pyridin-2-yl)amino)bis(dimethylamino)titanium;
In
tetrahydrofuran; hexane; toluene;
DOI:10.1002/chem.202003223
