bis<2-(1-hydroxy-1-methylethyl)-4-(1,1-dimethylethyl)-6-(hydroxymethyl)phenyl> sulfide

Base Information

• Chemical Name: bis<2-(1-hydroxy-1-methylethyl)-4-(1,1-dimethylethyl)-6-(hydroxymethyl)phenyl> sulfide
• CAS No.: 75893-97-9
• Molecular Formula: C₂₈H₄₂O₄S
• Molecular Weight: 474.705
• Mol file: 75893-97-9.mol

Synonyms:bis<2-(1-hydroxy-1-methylethyl)-4-(1,1-dimethylethyl)-6-(hydroxymethyl)phenyl> sulfide

Chemical Property of bis<2-(1-hydroxy-1-methylethyl)-4-(1,1-dimethylethyl)-6-(hydroxymethyl)phenyl> sulfide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of bis<2-(1-hydroxy-1-methylethyl)-4-(1,1-dimethylethyl)-6-(hydroxymethyl)phenyl> sulfide

There total 7 articles about bis<2-(1-hydroxy-1-methylethyl)-4-(1,1-dimethylethyl)-6-(hydroxymethyl)phenyl> sulfide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

bis<2-(1-hydroxy-1-methylethyl)-4-(1,1-dimethylethyl)-6-carbethoxyphenyl> sulphide (62558-12-7) → bis<2-(1-hydroxy-1-methylethyl)-4-(1,1-dimethylethyl)-6-(hydroxymethyl)phenyl> sulfide (75893-97-9)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether; for 10h; Heating;

DOI:10.1021/ja00391a023

Reference yield:

2-mercapto-5-tert-butylisophthalic acid (64407-86-9) → bis<2-(1-hydroxy-1-methylethyl)-4-(1,1-dimethylethyl)-6-(hydroxymethyl)phenyl> sulfide (75893-97-9)

Guidance literature:

Multi-step reaction with 5 steps

1: 70 percent / NaOH, copper-bronze powder / dimethylformamide / 14 h / Heating

2: SOCl₂ / Heating

3: pyridine / 1 h / Heating

4: 78.4 percent / diethyl ether / 3 h / Heating

5: 74 percent / LiAlH₄ / diethyl ether / 10 h / Heating

With pyridine; sodium hydroxide; lithium aluminium tetrahydride; thionyl chloride; copper; In diethyl ether; N,N-dimethyl-formamide;

DOI:10.1021/ja00391a023

Reference yield:

C32H42O8S (62558-15-0) → bis<2-(1-hydroxy-1-methylethyl)-4-(1,1-dimethylethyl)-6-(hydroxymethyl)phenyl> sulfide (75893-97-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 78.4 percent / diethyl ether / 3 h / Heating

2: 74 percent / LiAlH₄ / diethyl ether / 10 h / Heating

With lithium aluminium tetrahydride; In diethyl ether;

DOI:10.1021/ja00391a023

upstream raw materials:

bis<2-(1-hydroxy-1-methylethyl)-4-(1,1-dimethylethyl)-6-carbethoxyphenyl> sulphide

bis<5-(1,1-dimethylethyl)-3-(1-hydroxy-1-methylethyl)benzoato(3-)-C²,O¹,O³>(OC-6-22')sulfur

2-mercapto-5-tert-butylisophthalic acid

C₃₂H₄₂O₈S

Downstream raw materials:

2-[5-tert-Butyl-2-(4-tert-butyl-2-hydroxymethyl-6-isopropenyl-benzenesulfonyl)-3-hydroxymethyl-phenyl]-propan-2-ol

Bis<2-(1-methoxy-1-methylethyl)-4-(1,1-dimethylethyl)-6-(methoxymethyl)phenyl>sulfide

2-{5-tert-Butyl-2-[4-tert-butyl-2-hydroxymethyl-6-(1-hydroxy-1-methyl-ethyl)-benzenesulfonyl]-3-hydroxymethyl-phenyl}-propan-2-ol

2-[5-tert-Butyl-2-(5-tert-butyl-1-chloro-7-hydroxymethyl-3,3-dimethyl-1,3-dihydro-1λ⁴-benzo[c][1,2]oxathiol-1-yl)-3-hydroxymethyl-phenyl]-propan-2-ol