2-(2-hydroxy-3-nitrophenyl)-N-(trifluoroacetyl)ethylamine

Base Information

Chemical Name:2-(2-hydroxy-3-nitrophenyl)-N-(trifluoroacetyl)ethylamine
CAS No.:108773-05-3
Molecular Formula:C₁₀H₉F₃N₂O₄
Molecular Weight:278.188
Hs Code.:
DSSTox Substance ID:DTXSID001181271

Synonyms:2-(2-hydroxy-3-nitrophenyl)-N-(trifluoroacetyl)ethylamine;108773-05-3;SCHEMBL10866369;XBEUCGSLYWVQLG-UHFFFAOYSA-N;DTXSID001181271;2,2,2-trifluoro-N-[2-(2-hydroxy-3-nitrophenyl)ethyl]acetamide

Suppliers and Price of 2-(2-hydroxy-3-nitrophenyl)-N-(trifluoroacetyl)ethylamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-(2-hydroxy-3-nitrophenyl)-N-(trifluoroacetyl)ethylamine

Chemical Property:

XLogP3:2.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:3
Exact Mass:278.05144126
Heavy Atom Count:19
Complexity:343

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC(=C(C(=C1)[N+](=O)[O-])O)CCNC(=O)C(F)(F)F

Technology Process of 2-(2-hydroxy-3-nitrophenyl)-N-(trifluoroacetyl)ethylamine

There total 2 articles about 2-(2-hydroxy-3-nitrophenyl)-N-(trifluoroacetyl)ethylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 30.0%

: 108773-31-5
2,2,2-trifluoro-N-(2-hydroxyphenethyl)acetamide

: 108773-05-3
2-(2-hydroxy-3-nitrophenyl)-N-(trifluoroacetyl)ethylamine

Guidance literature:: With hydrogenchloride; sodium nitrate; lanthanum(III) nitrate; In diethyl ether; for 18h; Ambient temperature;
DOI:10.1021/jm00390a009

Reference yield:

: 13062-80-1
2-(2-hydroxyphenyl)ethylamine hydrobromide

: 108773-05-3
2-(2-hydroxy-3-nitrophenyl)-N-(trifluoroacetyl)ethylamine

Guidance literature:: Multi-step reaction with 2 steps

1: 94 percent / diethyl ether / 1 h / Ambient temperature

2: 30 percent / NaNO₃, La(NO₃)3*6H₂O, 6 N HCl / diethyl ether / 18 h / Ambient temperature

With hydrogenchloride; sodium nitrate; lanthanum(III) nitrate; In diethyl ether;
DOI:10.1021/jm00390a009