1-(Biphenyl-4-yl-phenyl-methyl)-piperazine

Base Information

Chemical Name:1-(Biphenyl-4-yl-phenyl-methyl)-piperazine
CAS No.:518005-84-0
Molecular Formula:C₂₃H₂₄N₂
Molecular Weight:328.457
Hs Code.:2933599090
DSSTox Substance ID:DTXSID30398169
Mol file:518005-84-0.mol

Synonyms:1-(Biphenyl-4-yl-phenyl-methyl)-piperazine;518005-84-0;1-[phenyl-(4-phenylphenyl)methyl]piperazine;DTXSID30398169

Suppliers and Price of 1-(Biphenyl-4-yl-phenyl-methyl)-piperazine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
1-([1,1'-Biphenyl]-4-yl(phenyl)methyl)piperazine 97%
1g
$ 761.00

American Custom Chemicals Corporation
1-(BIPHENYL-4-YL-PHENYL-METHYL)-PIPERAZINE 95.00%
1G
$ 1052.67

Total 4 raw suppliers

Chemical Property of 1-(Biphenyl-4-yl-phenyl-methyl)-piperazine

Chemical Property:

PSA：15.27000
LogP:4.61490
XLogP3:4.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:328.193948774
Heavy Atom Count:25
Complexity:370

Purity/Quality:

98% ^*data from raw suppliers

1-([1,1'-Biphenyl]-4-yl(phenyl)methyl)piperazine 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CCN1)C(C2=CC=CC=C2)C3=CC=C(C=C3)C4=CC=CC=C4

Technology Process of 1-(Biphenyl-4-yl-phenyl-methyl)-piperazine

There total 3 articles about 1-(Biphenyl-4-yl-phenyl-methyl)-piperazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 7598-80-3
4-phenylbenzhydrol

: 518005-84-0
1-(biphenyl-4-yl-phenyl-methyl)-piperazine

Guidance literature:: Multi-step reaction with 2 steps

1: SOCl₂ / CH₂Cl₂ / 1 h / 0 °C

2: acetonitrile / Heating

With thionyl chloride; In dichloromethane; acetonitrile;
DOI:10.1016/j.bmcl.2004.02.092

Reference yield:

: phenylmagnesium bromide

: 518005-84-0
1-(biphenyl-4-yl-phenyl-methyl)-piperazine

Guidance literature:: Multi-step reaction with 3 steps

1: tetrahydrofuran / 1 h / 20 °C

2: SOCl₂ / CH₂Cl₂ / 1 h / 0 °C

3: acetonitrile / Heating

With thionyl chloride; In tetrahydrofuran; dichloromethane; acetonitrile;
DOI:10.1016/j.bmcl.2004.02.092

Reference yield:

: 3218-36-8
4-Phenylbenzaldehyde

: 518005-84-0
1-(biphenyl-4-yl-phenyl-methyl)-piperazine

Guidance literature:: Multi-step reaction with 3 steps

1: tetrahydrofuran / 1 h / 20 °C

2: SOCl₂ / CH₂Cl₂ / 1 h / 0 °C

3: acetonitrile / Heating

With thionyl chloride; In tetrahydrofuran; dichloromethane; acetonitrile;
DOI:10.1016/j.bmcl.2004.02.092