N-<2-(phenylsulfinyl)-2-(2,5-dimethoxyphenyl)ethyl>formamide

Base Information

• Chemical Name: N-<2-(phenylsulfinyl)-2-(2,5-dimethoxyphenyl)ethyl>formamide
• CAS No.: 108536-23-8
• Molecular Formula: C₁₇H₁₉NO₄S
• Molecular Weight: 333.408
• Mol file: 108536-23-8.mol

Synonyms:N-<2-(phenylsulfinyl)-2-(2,5-dimethoxyphenyl)ethyl>formamide

Chemical Property of N-<2-(phenylsulfinyl)-2-(2,5-dimethoxyphenyl)ethyl>formamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-<2-(phenylsulfinyl)-2-(2,5-dimethoxyphenyl)ethyl>formamide

There total 5 articles about N-<2-(phenylsulfinyl)-2-(2,5-dimethoxyphenyl)ethyl>formamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

N-<2-(phenylthio)-2-(2,5-dimethoxyphenyl)ethyl>formamide (108536-20-5) → N-<2-(phenylsulfinyl)-2-(2,5-dimethoxyphenyl)ethyl>formamide (108536-23-8)

Guidance literature:

With sodium periodate; In methanol; for 24h; Ambient temperature;

DOI:10.1021/jo00389a062

Reference yield:

β-dimethoxy-2,5 phenyl nitro ethylene (108536-18-1) → N-<2-(phenylsulfinyl)-2-(2,5-dimethoxyphenyl)ethyl>formamide (108536-23-8)

Guidance literature:

Multi-step reaction with 4 steps

1: 100 percent / DMAP / tetrahydrofuran / 6 h / Heating

2: 76 percent / LAH / tetrahydrofuran; diethyl ether / 24 h / Heating

3: 91 percent / tetrahydrofuran / -15 - 20 °C

4: 100 percent / aq. sodium metaperiodate / methanol / 24 h / Ambient temperature

With dmap; sodium periodate; lithium aluminium tetrahydride; In tetrahydrofuran; methanol; diethyl ether;

DOI:10.1021/jo00389a062

Reference yield:

1-(2,5-dimethoxyphenyl)-1-(phenylthio)-2-aminoethane (108536-22-7) → N-<2-(phenylsulfinyl)-2-(2,5-dimethoxyphenyl)ethyl>formamide (108536-23-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 91 percent / tetrahydrofuran / -15 - 20 °C

2: 100 percent / aq. sodium metaperiodate / methanol / 24 h / Ambient temperature

With sodium periodate; In tetrahydrofuran; methanol;

DOI:10.1021/jo00389a062

upstream raw materials:

N-<2-(phenylthio)-2-(2,5-dimethoxyphenyl)ethyl>formamide

β-dimethoxy-2,5 phenyl nitro ethylene

1-(2,5-dimethoxyphenyl)-1-(phenylthio)-2-aminoethane

2,5-dimethoxybenzaldehyde

Downstream raw materials:

(E)-N-[2-(2,5-dimethoxyphenyl)ethenyl] formamide

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