phenyl 4-(N-benzylformamido)-4,6-dideoxy-3-C-methyl-1-thio-α-L-mannopyranoside

Base Information

Chemical Name:phenyl 4-(N-benzylformamido)-4,6-dideoxy-3-C-methyl-1-thio-α-L-mannopyranoside
CAS No.:131087-42-8
Molecular Formula:C₂₁H₂₅NO₄S
Molecular Weight:387.5
Hs Code.:

Synonyms:phenyl 4-(N-benzylformamido)-4,6-dideoxy-3-C-methyl-1-thio-α-L-mannopyranoside

Suppliers and Price of phenyl 4-(N-benzylformamido)-4,6-dideoxy-3-C-methyl-1-thio-α-L-mannopyranoside

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of phenyl 4-(N-benzylformamido)-4,6-dideoxy-3-C-methyl-1-thio-α-L-mannopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of phenyl 4-(N-benzylformamido)-4,6-dideoxy-3-C-methyl-1-thio-α-L-mannopyranoside

There total 7 articles about phenyl 4-(N-benzylformamido)-4,6-dideoxy-3-C-methyl-1-thio-α-L-mannopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 131087-41-7
phenyl 4-(N-benzylformamido)-4,6-dideoxy-2,3-O-isopropylidene-3-C-methyl-1-thio-α-L-mannopyranoside

: 131087-42-8
phenyl 4-(N-benzylformamido)-4,6-dideoxy-3-C-methyl-1-thio-α-L-mannopyranoside

Guidance literature:: With acetic acid; at 80 ℃; for 7.5h;
DOI:10.1016/0008-6215(90)80164-X

Reference yield:

: 131087-35-9
phenyl 2,3-O-isopropylidene-1-thio-α-L-rhamnopyranoside

: 131087-42-8
phenyl 4-(N-benzylformamido)-4,6-dideoxy-3-C-methyl-1-thio-α-L-mannopyranoside

Guidance literature:: Multi-step reaction with 7 steps

1: 72 percent / pyridinium chlorochromate / CH₂Cl₂ / 2 h / Ambient temperature

2: 1) lithium di-isopropylamide, 2) hexamethylphosphoric triamide / 1) oxolane, -76 deg C, 1 h, 2) 5 h

3: 64 percent / hydroxylamine hydrochloride, NaCO₃ / ethanol / 20 h / Heating

4: 30 percent / LiALH₄ / tetrahydrofuran / 4 h / 100 °C

5: 70 percent / 1-(3-dimethylaminopropyl)-3-ethylcarbodi-imide / CH₂Cl₂ / 2 h / Ambient temperature

6: 1) NaH / 1) DMF, r.t., 1 h, 2) 20 min

7: 80 percent / aq. 70percent acetic acid / 7.5 h / 80 °C

With N,N,N,N,N,N-hexamethylphosphoric triamide; lithium aluminium tetrahydride; hydroxylamine hydrochloride; sodium hydride; acetic acid; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; pyridinium chlorochromate; lithium diisopropyl amide; In tetrahydrofuran; ethanol; dichloromethane;
DOI:10.1016/0008-6215(90)80164-X

Reference yield:

: 131087-39-3
phenyl 4-amino-4,6-dideoxy-2,3-O-isopropylidene-3-C-methyl-1-thio-α-L-mannopyranoside

: 131087-42-8
phenyl 4-(N-benzylformamido)-4,6-dideoxy-3-C-methyl-1-thio-α-L-mannopyranoside

Guidance literature:: Multi-step reaction with 3 steps

1: 70 percent / 1-(3-dimethylaminopropyl)-3-ethylcarbodi-imide / CH₂Cl₂ / 2 h / Ambient temperature

2: 1) NaH / 1) DMF, r.t., 1 h, 2) 20 min

3: 80 percent / aq. 70percent acetic acid / 7.5 h / 80 °C

With sodium hydride; acetic acid; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; In dichloromethane;
DOI:10.1016/0008-6215(90)80164-X