3-Amino-5-(2-methylphenyl)-1H-pyrazole

Base Information

Chemical Name:3-Amino-5-(2-methylphenyl)-1H-pyrazole
CAS No.:57860-42-1
Molecular Formula:C10H11N3
Molecular Weight:173.217
Hs Code.:2933199090
DSSTox Substance ID:DTXSID50973452
Wikidata:Q82957376
Mol file:57860-42-1.mol

Synonyms:57860-42-1;3-Amino-5-(2-methylphenyl)-1H-pyrazole;3-Amino-5-(2-methylphenyl)pyrazole;3-(2-methylphenyl)-1H-pyrazol-5-amine;5-(2-methylphenyl)-1H-pyrazol-3-amine;902835-99-8;5-o-Tolyl-2H-pyrazol-3-ylamine;3-o-tolyl-1h-pyrazol-5-amine;5-(o-Tolyl)-1H-pyrazol-3-amine;1H-Pyrazol-3-amine, 5-(methylphenyl)-;5-(2-METHYLPHENYL)-2H-PYRAZOL-3-AMINE;MFCD11054300;5-(2-methylphenyl)-1H-pyrazole-3-amine;3-Amino-5-o-tolyl-pyrazole;SCHEMBL1407405;5-o-tolyl-1H-pyrazol-3-amine;DTXSID50973452;5-o-Tolyl-1H-pyrazol-3-ylamine;CKQCUZKXAXOTEZ-UHFFFAOYSA-N;AMY20246;MFCD02664272;STK520698;AKOS000111385;AKOS000168608;FS-2070;SY011836;3-o-Tolyl-1H-pyrazol-5-amine, AldrichCPR;BB 0238515;BB 0249386;FT-0604331;FT-0726345;EN300-61271;A19284;A831643;J-517892;5-(2-Methylphenyl)-1,2-dihydro-3H-pyrazol-3-imine;Z317042210

Suppliers and Price of 3-Amino-5-(2-methylphenyl)-1H-pyrazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
3-o-Tolyl-1H-pyrazol-5-amine Aldrich
1g
$ 140.00

Labseeker
5-o-Tolyl-2H-pyrazol-3-ylamine 95
10g
$ 1767.00

Labseeker
5-o-Tolyl-2H-pyrazol-3-ylamine 95
5g
$ 1333.00

Crysdot
5-(o-Tolyl)-1H-pyrazol-3-amine 97%
1g
$ 135.00

Crysdot
5-(o-Tolyl)-1H-pyrazol-3-amine 97%
5g
$ 275.00

Crysdot
5-(o-Tolyl)-1H-pyrazol-3-amine 97%
25g
$ 700.00

Chemenu
5-(o-Tolyl)-1H-pyrazol-3-amine 97%
25g
$ 757.00

Chemenu
5-(o-Tolyl)-1H-pyrazol-3-amine 97%
5g
$ 290.00

Chemenu
5-(o-Tolyl)-1H-pyrazol-3-amine 97%
10g
$ 570.00

American Custom Chemicals Corporation
3-AMINO-5-(2-METHYLPHENYL)-1H-PYRAZOLE 95.00%
5MG
$ 501.66

Total 17 raw suppliers

Chemical Property of 3-Amino-5-(2-methylphenyl)-1H-pyrazole

Chemical Property:

Boiling Point:414.5±33.0 °C(Predicted)
PKA:14?+-.0.10(Predicted)
PSA：54.70000
Density:1.196±0.06 g/cm3(Predicted)
LogP:2.54850
XLogP3:1.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:173.095297364
Heavy Atom Count:13
Complexity:172

Purity/Quality:

97% ^*data from raw suppliers

3-o-Tolyl-1H-pyrazol-5-amine Aldrich ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn
Hazard Codes:Xn
Statements: 22

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=CC=C1C2=CC(=NN2)N

Technology Process of 3-Amino-5-(2-methylphenyl)-1H-pyrazole

There total 3 articles about 3-Amino-5-(2-methylphenyl)-1H-pyrazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 35276-81-4
3-oxo-3-(o-tolyl)propanenitrile

: 57860-42-1,902835-99-8
3-amino-5-(2-methyl-phenyl)-pyrazole

Guidance literature:: With hydrazine; In ethanol; at 70 ℃; for 16h;

Reference yield:

: 35276-81-4
3-oxo-3-(o-tolyl)propanenitrile

: 57860-42-1
5-o-Tolyl-2H-pyrazol-3-ylamine

Guidance literature:: With hydrazine hydrate; In ethanol; for 5h; Heating;
DOI:10.1016/j.bmc.2006.07.023

Reference yield:

: 89-71-4
2-Methyl-benzoic acid methyl ester

: 57860-42-1
5-o-Tolyl-2H-pyrazol-3-ylamine

Guidance literature:: Multi-step reaction with 2 steps

1.1: lithium diisopropylamide / tetrahydrofuran / -78 °C

1.2: tetrahydrofuran / -78 - 20 °C

2.1: hydrazine monohydrate / ethanol / 5 h / Heating

With hydrazine hydrate; lithium diisopropyl amide; In tetrahydrofuran; ethanol;
DOI:10.1016/j.bmc.2006.07.023