(2R,3S,4R,4aR,7aS)-3,4-Bis-benzyloxy-2-benzyloxymethyl-6-methyl-2,3,4,4a,5,7a-hexahydro-pyrano[2,3-b]pyrrole

Base Information

• Chemical Name: (2R,3S,4R,4aR,7aS)-3,4-Bis-benzyloxy-2-benzyloxymethyl-6-methyl-2,3,4,4a,5,7a-hexahydro-pyrano[2,3-b]pyrrole
• CAS No.: 913266-60-1
• Molecular Formula: C₃₀H₃₃NO₄
• Molecular Weight: 471.596
• Mol file: 913266-60-1.mol

Synonyms:(2R,3S,4R,4aR,7aS)-3,4-Bis-benzyloxy-2-benzyloxymethyl-6-methyl-2,3,4,4a,5,7a-hexahydro-pyrano[2,3-b]pyrrole

Chemical Property of (2R,3S,4R,4aR,7aS)-3,4-Bis-benzyloxy-2-benzyloxymethyl-6-methyl-2,3,4,4a,5,7a-hexahydro-pyrano[2,3-b]pyrrole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2R,3S,4R,4aR,7aS)-3,4-Bis-benzyloxy-2-benzyloxymethyl-6-methyl-2,3,4,4a,5,7a-hexahydro-pyrano[2,3-b]pyrrole

There total 1 articles about (2R,3S,4R,4aR,7aS)-3,4-Bis-benzyloxy-2-benzyloxymethyl-6-methyl-2,3,4,4a,5,7a-hexahydro-pyrano[2,3-b]pyrrole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

1-((2R,3R,4R,5S,6R)-2-Azido-4,5-bis-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-3-yl)-propan-2-one (857419-94-4) → (2R,3S,4R,4aR,7aS)-3,4-Bis-benzyloxy-2-benzyloxymethyl-6-methyl-2,3,4,4a,5,7a-hexahydro-pyrano[2,3-b]pyrrole (913266-60-1)

Guidance literature:

With water; In tetrahydrofuran; at 20 ℃; for 24h;

DOI:10.1016/j.carres.2006.07.005

Reference yield:

(2R,3S,4R,4aR,7aS)-3,4-Bis-benzyloxy-2-benzyloxymethyl-6-methyl-2,3,4,4a,5,7a-hexahydro-pyrano[2,3-b]pyrrole (913266-60-1) → 2-methyl-4-(1',2',4'-tri-benzyloxy-3'-hydroxy-butyl)pyrrolidine + 2-methyl-4-(1',2',4'-tri-benzyloxy-3'-hydroxy-butyl)pyrrolidine

Guidance literature:

With sodium tetrahydroborate; In methanol; at 20 ℃; for 16h; Title compound not separated from byproducts;

DOI:10.1016/j.carres.2006.07.005

upstream raw materials:

1-((2R,3R,4R,5S,6R)-2-Azido-4,5-bis-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-3-yl)-propan-2-one