(S)-2-Hydroxy-2-[(S)-1-((S)-toluene-4-sulfinyl)-ethyl]-pentanoic acid amide

Base Information

Chemical Name:(S)-2-Hydroxy-2-[(S)-1-((S)-toluene-4-sulfinyl)-ethyl]-pentanoic acid amide
CAS No.:200356-01-0
Molecular Formula:C₁₄H₂₁NO₃S
Molecular Weight:283.392
Hs Code.:

Synonyms:(S)-2-Hydroxy-2-[(S)-1-((S)-toluene-4-sulfinyl)-ethyl]-pentanoic acid amide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (S)-2-Hydroxy-2-[(S)-1-((S)-toluene-4-sulfinyl)-ethyl]-pentanoic acid amide

Chemical Property:

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Technology Process of (S)-2-Hydroxy-2-[(S)-1-((S)-toluene-4-sulfinyl)-ethyl]-pentanoic acid amide

There total 1 articles about (S)-2-Hydroxy-2-[(S)-1-((S)-toluene-4-sulfinyl)-ethyl]-pentanoic acid amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 144694-77-9,144786-50-5
(S₂,R_S)-2-hydroxy-2-{1-[(4-methylphenyl)sulfinyl]ethyl}pentanenitrile

: 200356-01-0
(S)-2-Hydroxy-2-[(S)-1-((S)-toluene-4-sulfinyl)-ethyl]-pentanoic acid amide

: 200356-00-9
(S)-2-Hydroxy-2-[(R)-1-((S)-toluene-4-sulfinyl)-ethyl]-pentanoic acid amide

Guidance literature:: With methanol; tetrafluoroboric acid; Multistep reaction; 1.) CH₂Cl₂, RT, 3 h, 2.) CH₂Cl₂, RT, 3 h;
DOI:10.1016/S0957-4166(97)00457-6

Reference yield: 84.0%

: 200356-01-0
(S)-2-Hydroxy-2-[(S)-1-((S)-toluene-4-sulfinyl)-ethyl]-pentanoic acid amide

: 144694-84-8
(S₂,S₃)-2-hydroxy-2-{[1-(4-methylphenyl)sulfenyl]ethyl}pentanamide

Guidance literature:: With boron trifluoride diethyl etherate; sodium iodide; In acetonitrile;
DOI:10.1016/S0957-4166(97)00457-6

Reference yield:

: 200356-01-0
(S)-2-Hydroxy-2-[(S)-1-((S)-toluene-4-sulfinyl)-ethyl]-pentanoic acid amide

: 200356-08-7
(2R,3R)-3-methyl-2-n-propyloxirane-2-carboxamide

Guidance literature:: Multi-step reaction with 2 steps

1: 84 percent / BF₃*Et₂O, NaI / acetonitrile

2: 1.) Me₃OBF₄, 2.) aq. K₂CO₃ / 1.) CH₂Cl₂, RT, 3 h, 2.) CH₂Cl₂, RT, 17 h

With boron trifluoride diethyl etherate; trimethoxonium tetrafluoroborate; potassium carbonate; sodium iodide; In acetonitrile;
DOI:10.1016/S0957-4166(97)00457-6