Technology Process of C28H27IO6
There total 4 articles about C28H27IO6 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
C28H29NO6;
With
hydrogenchloride;
In
tetrahydrofuran; water;
at 0 ℃;
for 0.25h;
With
sodium nitrite;
In
tetrahydrofuran; water;
at 0 ℃;
for 0.666667h;
With
potassium iodide;
In
tetrahydrofuran; water;
at 0 - 20 ℃;
for 2.6h;
DOI:10.1021/ja312148q
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: pyridine / 15 h / 20 °C / Inert atmosphere
2.1: triethylamine; palladium 10% on activated carbon; hydrogen / ethyl acetate / 1 h / 20 °C
3.1: hydrogenchloride / tetrahydrofuran; water / 0.25 h / 0 °C
3.2: 0.67 h / 0 °C
3.3: 2.6 h / 0 - 20 °C
With
pyridine; hydrogenchloride; palladium 10% on activated carbon; hydrogen; triethylamine;
In
tetrahydrofuran; water; ethyl acetate;
3.2: |Sandmeyer Reaction / 3.3: |Sandmeyer Reaction;
DOI:10.1021/ja312148q
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: pyridine / 15 h / 20 °C / Inert atmosphere
2.1: triethylamine; palladium 10% on activated carbon; hydrogen / ethyl acetate / 1 h / 20 °C
3.1: hydrogenchloride / tetrahydrofuran; water / 0.25 h / 0 °C
3.2: 0.67 h / 0 °C
3.3: 2.6 h / 0 - 20 °C
With
pyridine; hydrogenchloride; palladium 10% on activated carbon; hydrogen; triethylamine;
In
tetrahydrofuran; water; ethyl acetate;
3.2: |Sandmeyer Reaction / 3.3: |Sandmeyer Reaction;
DOI:10.1021/ja312148q
