2-IODO-3-METHYLBENZONITRILE

Base Information

• Chemical Name: 2-IODO-3-METHYLBENZONITRILE
• CAS No.: 52107-70-7
• Molecular Formula: C8H6IN
• Molecular Weight: 243.047
• Hs Code.: 2926909090
• Mol file: 52107-70-7.mol

Synonyms:2-IODO-3-METHYLBENZONITRILE

Chemical Property of 2-IODO-3-METHYLBENZONITRILE

Chemical Property:

• Vapor Pressure: 0.000971mmHg at 25°C
• Refractive Index: 1.638
• Boiling Point: 302.7°Cat760mmHg
• Flash Point: 136.9°C
• PSA: 23.79000
• Density: 1.78g/cm³
• LogP: 2.47128

Purity/Quality:

98%Min ^*data from raw suppliers

2-Iodo-3-methylbenzonitrile 98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-IODO-3-METHYLBENZONITRILE

There total 1 articles about 2-IODO-3-METHYLBENZONITRILE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-amino-3-methylbenzonitrile (69797-49-5) → 2-iodo-3-methylbenzonitrile (52107-70-7)

Guidance literature:

Multistep reaction; (i) NaNO₂, aq. H₂SO₄, (ii) KI;

Reference yield: 53.0%

2-iodo-3-methylbenzonitrile (52107-70-7) → (2-iodo-3-methylphenyl)methanamine

Guidance literature:

With lithium aluminium tetrahydride; sulfuric acid; In tetrahydrofuran; at 0 ℃;

DOI:10.1016/j.ejmech.2018.01.053

Reference yield: 45.0%

2-iodo-3-methylbenzonitrile (52107-70-7) + acetic acid (64-19-7,77671-22-8) → (2-cyano-6-methylphenyl)-l3-iodanediyl diacetate

Guidance literature:

2-iodo-3-methylbenzonitrile; With oxone||potassium monopersulfate triple salt; trifluoroacetic acid; In dichloromethane; at 20 ℃; for 1h; Inert atmosphere;

acetic acid; at 20 ℃; for 1h; Inert atmosphere;

DOI:10.1002/anie.201909019

upstream raw materials:

2-amino-3-methylbenzonitrile

Downstream raw materials:

C₂₅H₁₉BrN₂O₂

C₂₅H₁₉IN₂O₂

1-(benzhydrylidene-amino)-3-methylene-indane-4-carbonitrile

2-bromo-3-(bromomethyl)benzonitrile