(R)-4-[(3R,5R,8R,9S,10S,12S,13S,14S,16S,17S)-3,12-Dihydroxy-16-(1-hydroxy-cyclohexyl)-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-17-yl]-pentanoic acid

Base Information

• Chemical Name: (R)-4-[(3R,5R,8R,9S,10S,12S,13S,14S,16S,17S)-3,12-Dihydroxy-16-(1-hydroxy-cyclohexyl)-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-17-yl]-pentanoic acid
• CAS No.: 77522-07-7
• Molecular Formula: C₃₀H₅₀O₅
• Molecular Weight: 490.724
• Mol file: 77522-07-7.mol

Synonyms:(R)-4-[(3R,5R,8R,9S,10S,12S,13S,14S,16S,17S)-3,12-Dihydroxy-16-(1-hydroxy-cyclohexyl)-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-17-yl]-pentanoic acid

Chemical Property of (R)-4-[(3R,5R,8R,9S,10S,12S,13S,14S,16S,17S)-3,12-Dihydroxy-16-(1-hydroxy-cyclohexyl)-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-17-yl]-pentanoic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (R)-4-[(3R,5R,8R,9S,10S,12S,13S,14S,16S,17S)-3,12-Dihydroxy-16-(1-hydroxy-cyclohexyl)-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-17-yl]-pentanoic acid

There total 1 articles about (R)-4-[(3R,5R,8R,9S,10S,12S,13S,14S,16S,17S)-3,12-Dihydroxy-16-(1-hydroxy-cyclohexyl)-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-17-yl]-pentanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 10.0%

2:1 deoxycholic acid-cyclohexanone complex (95484-92-7) → 3α,5β,12α-trihydroxy-5β-cholan-24-oic acid (58678-36-7) + (R)-4-[(3R,5R,8R,9S,10S,12S,13S,14S,16S,17S)-3,12-Dihydroxy-16-(1-hydroxy-cyclohexyl)-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-17-yl]-pentanoic acid (77522-07-7)

Guidance literature:

With air; In solid; for 240h; Ambient temperature; Irradiation;

DOI:10.1021/ja00299a047

Reference yield:

(R)-4-[(3R,5R,8R,9S,10S,12S,13S,14S,16S,17S)-3,12-Dihydroxy-16-(1-hydroxy-cyclohexyl)-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-17-yl]-pentanoic acid (77522-07-7) → (R)-4-((3R,5R,8R,9S,10S,12S,13S,14S,17S)-16-Cyclohexylidene-3,12-dihydroxy-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-17-yl)-pentanoic acid (95484-88-1)

Guidance literature:

With silica gel; iron(III) chloride; In diethyl ether; Yield given;

DOI:10.1021/ja00299a047

upstream raw materials:

2:1 deoxycholic acid-cyclohexanone complex

Downstream raw materials:

(R)-4-((3R,5R,8R,9S,10S,12S,13S,14S,17S)-16-Cyclohexylidene-3,12-dihydroxy-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-17-yl)-pentanoic acid