C₁₈H₂₀N₂O

Base Information

• Chemical Name: C₁₈H₂₀N₂O
• CAS No.: 1387007-03-5
• Molecular Formula: C₁₈H₂₀N₂O
• Molecular Weight: 280.37
• Mol file: 1387007-03-5.mol

Synonyms:C₁₈H₂₀N₂O

Chemical Property of C₁₈H₂₀N₂O

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₈H₂₀N₂O

There total 9 articles about C₁₈H₂₀N₂O which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C20H24N2O2 → C18H20N2O (1387007-03-5)

Guidance literature:

C₂₀H₂₄N₂O₂; With hydrogenchloride; water; at 20 ℃; for 10h;

With sodium hydroxide; In water; pH=7;

DOI:10.1016/j.tetasy.2012.05.012

Reference yield:

C20H23NO2 (1387007-01-3) → C18H20N2O (1387007-03-5)

Guidance literature:

Multi-step reaction with 4 steps

1.1: potassium permanganate / water; tert-butyl alcohol / 12 h / 75 - 80 °C

2.1: ammonium hydroxide / methanol; water / 72 h / 20 °C

3.1: palladium 10% on activated carbon; ammonium formate / methanol; water / 72 h / 20 °C

4.1: hydrogenchloride; water / 10 h / 20 °C

4.2: pH 7

With hydrogenchloride; ammonium hydroxide; potassium permanganate; palladium 10% on activated carbon; water; ammonium formate; In methanol; water; tert-butyl alcohol;

DOI:10.1016/j.tetasy.2012.05.012

Reference yield:

1-<2-(2-Methoxyphenyl)-2-oxyethyl>pyridinium iodide → C18H20N2O (1387007-03-5)

Guidance literature:

Multi-step reaction with 7 steps

1.1: sodium acetate; acetic acid / 100 - 110 °C / Inert atmosphere

1.2: 20 °C

2.1: boron tribromide / dichloromethane / 5 h / 0 - 20 °C / Inert atmosphere

2.2: 0 °C / Inert atmosphere

2.3: pH 7

3.1: sodium hydride / tetrahydrofuran; mineral oil / 0.5 h / 0 °C / Inert atmosphere

3.2: 3 h / 0 - 20 °C / Inert atmosphere

4.1: potassium permanganate / water; tert-butyl alcohol / 12 h / 75 - 80 °C

5.1: ammonium hydroxide / methanol; water / 72 h / 20 °C

6.1: palladium 10% on activated carbon; ammonium formate / methanol; water / 72 h / 20 °C

7.1: hydrogenchloride; water / 10 h / 20 °C

7.2: pH 7

With hydrogenchloride; ammonium hydroxide; potassium permanganate; palladium 10% on activated carbon; water; ammonium formate; sodium acetate; boron tribromide; sodium hydride; acetic acid; In tetrahydrofuran; methanol; dichloromethane; water; mineral oil; tert-butyl alcohol;

DOI:10.1016/j.tetasy.2012.05.012

upstream raw materials:

2-Methoxyacetophenone

C₂₀H₂₃NO₂

C₂₀H₂₁NO₃

o-hydroxyacetophenone

Refernces