4-[1-benzyl-5-(4-fluoro-benzylsulfamoyl)-1H-benzoimidazol-2-yl]-butyric acid methyl ester

Base Information

Chemical Name:4-[1-benzyl-5-(4-fluoro-benzylsulfamoyl)-1H-benzoimidazol-2-yl]-butyric acid methyl ester
CAS No.:845833-72-9
Molecular Formula:C₂₆H₂₆FN₃O₄S
Molecular Weight:495.575
Hs Code.:

4-[1-benzyl-5-(4-fluoro-benzylsulfamoyl)-1<i>H</i>-benzoimidazol-2-yl]-butyric acid methyl ester

Synonyms:4-[1-benzyl-5-(4-fluoro-benzylsulfamoyl)-1H-benzoimidazol-2-yl]-butyric acid methyl ester

Suppliers and Price of 4-[1-benzyl-5-(4-fluoro-benzylsulfamoyl)-1H-benzoimidazol-2-yl]-butyric acid methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4-[1-benzyl-5-(4-fluoro-benzylsulfamoyl)-1H-benzoimidazol-2-yl]-butyric acid methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-[1-benzyl-5-(4-fluoro-benzylsulfamoyl)-1H-benzoimidazol-2-yl]-butyric acid methyl ester

There total 3 articles about 4-[1-benzyl-5-(4-fluoro-benzylsulfamoyl)-1H-benzoimidazol-2-yl]-butyric acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 41.0%

: 860638-54-6
4-[2-benzylamino-5-(4-fluoro-benzylsulfamoyl)-phenylcarbamoyl]-butyric acid methyl ester

: 845833-72-9
4-[1-benzyl-5-(4-fluoro-benzylsulfamoyl)-1H-benzoimidazol-2-yl]-butyric acid methyl ester

Guidance literature:: With acetic acid; at 90 ℃;
DOI:10.1016/j.bmcl.2004.10.090

Reference yield:

: 1501-27-5
Pentanedioic acid, monomethyl ester

: 845833-72-9
4-[1-benzyl-5-(4-fluoro-benzylsulfamoyl)-1H-benzoimidazol-2-yl]-butyric acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: WSCI; HOBt; triethylamine / tetrahydrofuran / 20 °C

2: 41 percent / AcOH / 90 °C

With benzotriazol-1-ol; acetic acid; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; triethylamine; In tetrahydrofuran;
DOI:10.1016/j.bmcl.2004.10.090

Reference yield:

: 845833-87-6
3-amino-4-benzylamino-N-(4-fluoro-benzyl)-benzenesulfonamide

: 845833-72-9
4-[1-benzyl-5-(4-fluoro-benzylsulfamoyl)-1H-benzoimidazol-2-yl]-butyric acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: WSCI; HOBt; triethylamine / tetrahydrofuran / 20 °C

2: 41 percent / AcOH / 90 °C

With benzotriazol-1-ol; acetic acid; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; triethylamine; In tetrahydrofuran;
DOI:10.1016/j.bmcl.2004.10.090