4-(1-(phenylsulfonyl)-3-(thiazol-2-yl)-1H-pyrrolo[2,3-b]pyridin-5-yl)cyclohexanone

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Chemical Name:4-(1-(phenylsulfonyl)-3-(thiazol-2-yl)-1H-pyrrolo[2,3-b]pyridin-5-yl)cyclohexanone
CAS No.:1046793-06-9
Molecular Formula:C₂₂H₁₉N₃O₃S₂
Molecular Weight:437.543
Hs Code.:

Synonyms:4-(1-(phenylsulfonyl)-3-(thiazol-2-yl)-1H-pyrrolo[2,3-b]pyridin-5-yl)cyclohexanone

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Chemical Property of 4-(1-(phenylsulfonyl)-3-(thiazol-2-yl)-1H-pyrrolo[2,3-b]pyridin-5-yl)cyclohexanone

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Technology Process of 4-(1-(phenylsulfonyl)-3-(thiazol-2-yl)-1H-pyrrolo[2,3-b]pyridin-5-yl)cyclohexanone

There total 1 articles about 4-(1-(phenylsulfonyl)-3-(thiazol-2-yl)-1H-pyrrolo[2,3-b]pyridin-5-yl)cyclohexanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 1046793-05-8
2-(1-(phenylsulfonyl)-5-(1,4-dioxaspiro[4.5]decan-8-yl)-1H-pyrrolo[2,3-b]pyridin-3-yl)thiazole

: 1046793-06-9
4-(1-(phenylsulfonyl)-3-(thiazol-2-yl)-1H-pyrrolo[2,3-b]pyridin-5-yl)cyclohexanone

Guidance literature:: 2-(1-(phenylsulfonyl)-5-(1,4-dioxaspiro[4.5]decan-8-yl)-1H-pyrrolo[2,3-b]pyridin-3-yl)thiazole; With hydrogenchloride; water; In tetrahydrofuran; at 20 ℃; for 2h;

With water; sodium hydrogencarbonate; In tetrahydrofuran;

Reference yield: 50.0%

: 110-91-8,99108-56-2
morpholine

: 1046793-06-9
4-(1-(phenylsulfonyl)-3-(thiazol-2-yl)-1H-pyrrolo[2,3-b]pyridin-5-yl)cyclohexanone

: 4-((1s,4s)-4-(1-(phenylsulfonyl)-3-(thiazol-2-yl)-1H-pyrrolo[2,3-b]pyridin-5-yl)cyclohexyl)morpholine

: 4-((1r,4r)-4-(1-(phenylsulfonyl)-3-(thiazol-2-yl)-1H-pyrrolo[2,3-b]pyridin-5-yl)cyclohexyl)morpholine

Guidance literature:: morpholine; 4-(1-(phenylsulfonyl)-3-(thiazol-2-yl)-1H-pyrrolo[2,3-b]pyridin-5-yl)cyclohexanone; With acetic acid; In 1,2-dichloro-ethane; at 20 ℃; for 0.166667h;

With sodium tris(acetoxy)borohydride; In 1,2-dichloro-ethane;

With water; sodium hydrogencarbonate; In 1,2-dichloro-ethane;