1-(4-Chloro-benzyl)-piperidine-4-carboxylic acid (5-chloro-2-methoxy-4-nitro-phenyl)-amide

Base Information

• Chemical Name: 1-(4-Chloro-benzyl)-piperidine-4-carboxylic acid (5-chloro-2-methoxy-4-nitro-phenyl)-amide
• CAS No.: 69082-45-7
• Molecular Formula: C₂₀H₂₁Cl₂N₃O₄
• Molecular Weight: 438.31
• Mol file: 69082-45-7.mol

Synonyms:1-(4-Chloro-benzyl)-piperidine-4-carboxylic acid (5-chloro-2-methoxy-4-nitro-phenyl)-amide

Chemical Property of 1-(4-Chloro-benzyl)-piperidine-4-carboxylic acid (5-chloro-2-methoxy-4-nitro-phenyl)-amide

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 1-(4-Chloro-benzyl)-piperidine-4-carboxylic acid (5-chloro-2-methoxy-4-nitro-phenyl)-amide

There total 1 articles about 1-(4-Chloro-benzyl)-piperidine-4-carboxylic acid (5-chloro-2-methoxy-4-nitro-phenyl)-amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-(5-chloro-2-methoxyphenyl)-1-<(4-chlorophenyl)methyl>-4-piperidinecarboxamide hydrochloride (69082-62-8) → 1-(4-Chloro-benzyl)-piperidine-4-carboxylic acid (5-chloro-2-methoxy-4-nitro-phenyl)-amide (69082-45-7)

Guidance literature:

With sulfuric acid; nitric acid; In acetic acid; at 30 - 35 ℃; for 4h;

DOI:10.1021/jm00366a017

Reference yield:

1-(4-Chloro-benzyl)-piperidine-4-carboxylic acid (5-chloro-2-methoxy-4-nitro-phenyl)-amide (69082-45-7) → n-(4-amino-5-chloro-2-methoxyphenyl)-1-<(4-chlorophenyl)methyl>-4-piperidinecarboxamide (69082-51-5)

Guidance literature:

With hydrogenchloride; tin(ll) chloride; In acetic acid; Yield given; Ambient temperature;

DOI:10.1021/jm00366a017

upstream raw materials:

N-(5-chloro-2-methoxyphenyl)-1-<(4-chlorophenyl)methyl>-4-piperidinecarboxamide hydrochloride

Downstream raw materials:

n-(4-amino-5-chloro-2-methoxyphenyl)-1-<(4-chlorophenyl)methyl>-4-piperidinecarboxamide