4b-Chloro-11-methanesulfonyloxymethyl-5,6,8,9,10,11,12,13-octahydro-4bH-7,14-diaza-cycloundeca[a]indene-7,13-dicarboxylic acid 7-benzyl ester 13-methyl ester

Base Information

Chemical Name:4b-Chloro-11-methanesulfonyloxymethyl-5,6,8,9,10,11,12,13-octahydro-4bH-7,14-diaza-cycloundeca[a]indene-7,13-dicarboxylic acid 7-benzyl ester 13-methyl ester
CAS No.:107704-27-8
Molecular Formula:C₂₈H₃₃ClN₂O₇S
Molecular Weight:577.098
Hs Code.:

4b-Chloro-11-methanesulfonyloxymethyl-5,6,8,9,10,11,12,13-octahydro-4bH-7,14-diaza-cycloundeca[a]indene-7,13-dicarboxylic acid 7-benzyl ester 13-methyl ester

Synonyms:4b-Chloro-11-methanesulfonyloxymethyl-5,6,8,9,10,11,12,13-octahydro-4bH-7,14-diaza-cycloundeca[a]indene-7,13-dicarboxylic acid 7-benzyl ester 13-methyl ester

Suppliers and Price of 4b-Chloro-11-methanesulfonyloxymethyl-5,6,8,9,10,11,12,13-octahydro-4bH-7,14-diaza-cycloundeca[a]indene-7,13-dicarboxylic acid 7-benzyl ester 13-methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4b-Chloro-11-methanesulfonyloxymethyl-5,6,8,9,10,11,12,13-octahydro-4bH-7,14-diaza-cycloundeca[a]indene-7,13-dicarboxylic acid 7-benzyl ester 13-methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4b-Chloro-11-methanesulfonyloxymethyl-5,6,8,9,10,11,12,13-octahydro-4bH-7,14-diaza-cycloundeca[a]indene-7,13-dicarboxylic acid 7-benzyl ester 13-methyl ester

There total 12 articles about 4b-Chloro-11-methanesulfonyloxymethyl-5,6,8,9,10,11,12,13-octahydro-4bH-7,14-diaza-cycloundeca[a]indene-7,13-dicarboxylic acid 7-benzyl ester 13-methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 107688-23-3
2-benzyloxymethyl-2,3,4,5,6,7,8,13,13b-octahydro-1H-azepino<1',2':1,2>pyrido<3,4-b>indol

: 107704-27-8
4b-Chloro-11-methanesulfonyloxymethyl-5,6,8,9,10,11,12,13-octahydro-4bH-7,14-diaza-cycloundeca[a]indene-7,13-dicarboxylic acid 7-benzyl ester 13-methyl ester

Guidance literature:: Multi-step reaction with 9 steps

1: anhydrous sodium carbonate / tetrahydrofuran / 16 h / 50 °C

2: 98 percent / pyridine / 1 h / 40 °C

3: 98 percent / tetra-n-butyl ammonium bromide, sodium iodide / toluene / 2 h / Heating

4: 90 percent / sodium hydroxide, 30percent hydrogen peroxide / ethanol / 3 h / Ambient temperature

5: 77 percent / Amberlyst 15 / 120 h / 60 °C

6: acetic acid,H₂ / 10percent Pd/C / tetrahydrofuran / 25 h / 40 - 50 °C

7: sodium hydrogen carbonate sol., / CH₂Cl₂ / 15 h / Heating

8: 96 percent / triethylamine / CH₂Cl₂ / 2 h / 0 - 20 °C

9: triethylamine, tert-butylhypochlorit sol. / CH₂Cl₂; CCl₄ / -50 - -40 °C

With pyridine; sodium hydroxide; Amberlyst 15; tert-butylhypochlorite; tetrabutylammomium bromide; hydrogen; dihydrogen peroxide; sodium hydrogencarbonate; sodium carbonate; acetic acid; triethylamine; sodium iodide; palladium on activated charcoal; In tetrahydrofuran; tetrachloromethane; ethanol; dichloromethane; toluene;
DOI:10.1016/S0040-4020(01)86863-0

Reference yield:

: 107688-24-4,116260-72-1,116260-77-6
3-benzyloxycarbonyl-7-benzyloxymethyl-9-hydroxy-1,2,3,4,5,6,7,8,9,10-decahydroazacycloundecino<5,4-b>indol

: 107704-27-8
4b-Chloro-11-methanesulfonyloxymethyl-5,6,8,9,10,11,12,13-octahydro-4bH-7,14-diaza-cycloundeca[a]indene-7,13-dicarboxylic acid 7-benzyl ester 13-methyl ester

Guidance literature:: Multi-step reaction with 8 steps

1: 98 percent / pyridine / 1 h / 40 °C

2: 98 percent / tetra-n-butyl ammonium bromide, sodium iodide / toluene / 2 h / Heating

3: 90 percent / sodium hydroxide, 30percent hydrogen peroxide / ethanol / 3 h / Ambient temperature

4: 77 percent / Amberlyst 15 / 120 h / 60 °C

5: acetic acid,H₂ / 10percent Pd/C / tetrahydrofuran / 25 h / 40 - 50 °C

6: sodium hydrogen carbonate sol., / CH₂Cl₂ / 15 h / Heating

7: 96 percent / triethylamine / CH₂Cl₂ / 2 h / 0 - 20 °C

8: triethylamine, tert-butylhypochlorit sol. / CH₂Cl₂; CCl₄ / -50 - -40 °C

With pyridine; sodium hydroxide; Amberlyst 15; tert-butylhypochlorite; tetrabutylammomium bromide; hydrogen; dihydrogen peroxide; sodium hydrogencarbonate; acetic acid; triethylamine; sodium iodide; palladium on activated charcoal; In tetrahydrofuran; tetrachloromethane; ethanol; dichloromethane; toluene;
DOI:10.1016/S0040-4020(01)86863-0

Reference yield:

: 107688-24-4,116260-72-1,116260-77-6
3-benzyloxycarbonyl-7-benzyloxymethyl-9-hydroxy-1,2,3,4,5,6,7,8,9,10-decahydroazacycloundecino<5,4-b>indol

: 107704-27-8
4b-Chloro-11-methanesulfonyloxymethyl-5,6,8,9,10,11,12,13-octahydro-4bH-7,14-diaza-cycloundeca[a]indene-7,13-dicarboxylic acid 7-benzyl ester 13-methyl ester

Guidance literature:: Multi-step reaction with 8 steps

1: 97 percent / pyridine / 1 h / 40 °C

2: 96 percent / tetra-n-butyl ammonium bromide, sodium iodide / toluene / 2 h / Heating

3: 90 percent / sodium hydroxide, 30percent hydrogen peroxide / ethanol / 3 h / Ambient temperature

4: 77 percent / Amberlyst 15 / 120 h / 60 °C

5: acetic acid,H₂ / 10percent Pd/C / tetrahydrofuran / 25 h / 40 - 50 °C

6: sodium hydrogen carbonate sol., / CH₂Cl₂ / 15 h / Heating

7: 96 percent / triethylamine / CH₂Cl₂ / 2 h / 0 - 20 °C

8: triethylamine, tert-butylhypochlorit sol. / CH₂Cl₂; CCl₄ / -50 - -40 °C

With pyridine; sodium hydroxide; Amberlyst 15; tert-butylhypochlorite; tetrabutylammomium bromide; hydrogen; dihydrogen peroxide; sodium hydrogencarbonate; acetic acid; triethylamine; sodium iodide; palladium on activated charcoal; In tetrahydrofuran; tetrachloromethane; ethanol; dichloromethane; toluene;
DOI:10.1016/S0040-4020(01)86863-0