ethyl 3-([bis(dimethylamino)phosphoryl]oxy)-2-phenylquinoline-4-carboxylate

Base Information

Chemical Name:ethyl 3-([bis(dimethylamino)phosphoryl]oxy)-2-phenylquinoline-4-carboxylate
CAS No.:1224598-16-6
Molecular Formula:C₂₂H₂₆N₃O₄P
Molecular Weight:427.44
Hs Code.:

Synonyms:ethyl 3-([bis(dimethylamino)phosphoryl]oxy)-2-phenylquinoline-4-carboxylate

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Chemical Property of ethyl 3-([bis(dimethylamino)phosphoryl]oxy)-2-phenylquinoline-4-carboxylate

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MSDS Files:: SDS file from LookChem

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Technology Process of ethyl 3-([bis(dimethylamino)phosphoryl]oxy)-2-phenylquinoline-4-carboxylate

There total 1 articles about ethyl 3-([bis(dimethylamino)phosphoryl]oxy)-2-phenylquinoline-4-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 1224598-14-4
2-phenylquinolin-3-yl N,N,N',N'-tetramethyldiamidophosphate

: 623-49-4
ethyl cyanoformate

: 1224598-16-6
ethyl 3-([bis(dimethylamino)phosphoryl]oxy)-2-phenylquinoline-4-carboxylate

Guidance literature:: 2-phenylquinolin-3-yl N,N,N',N'-tetramethyldiamidophosphate; With 2,2,6,6-tetramethylpiperidinylmagnesium chloride lithium chloride complex; In tetrahydrofuran; at 25 ℃; Inert atmosphere;

ethyl cyanoformate; In tetrahydrofuran; at 25 ℃; regioselective reaction; Inert atmosphere;
DOI:10.1021/ol100453x