(S)-(-)-Mosapramine

Base Information

• Chemical Name: (S)-(-)-Mosapramine
• CAS No.: 120167-35-3
• Molecular Formula: C₂₈H₃₅ClN₄O
• Molecular Weight: 479.065
• Mol file: 120167-35-3.mol

Synonyms:5H-Dibenz[b,f]azepine,spiro[imidazo[1,2-a]pyridine-3(2H),4'-piperidin]-2-one deriv.;(S)-(-)-Mosapramine

Chemical Property of (S)-(-)-Mosapramine

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of (S)-(-)-Mosapramine

There total 2 articles about (S)-(-)-Mosapramine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-chloro-5-(3-methanesulfonyloxypropyl)-10,11-dihydro-5H-dibenzazepine (123435-16-5) + (R)-(-)-2-oxo-1,2,3,5,6,7,8,8a-octahydroimidazo<1,2-a>pyridine-3-spiro-4'-piperidine → (R)-(-)-3-chloro-5-<3-(2-oxo-1,2,3,5,6,7,8,8a-octahydroimidazo<1,2-a>pyridine-3-spiro-4'-piperidino)propyl>-10,11-dihydro-5H-dibenzazepine (120167-35-3,120181-35-3,89419-40-9)

Guidance literature:

With triethylamine; In chloroform; for 5h; Heating;

DOI:10.1248/cpb.41.1074

Reference yield:

3-chloro-5-(3-methanesulfonyloxypropyl)-10,11-dihydro-5H-dibenzazepine (123435-16-5) + (S)-(+)-2-oxo-1,2,3,5,6,7,8,8a-octahydroimidazo<1,2-a>pyridine-3-spiro-4'-piperidine → (S)-(+)-3-chloro-5-<3-(2-oxo-1,2,3,5,6,7,8,8a-octahydroimidazo<1,2-a>pyridine-3-spiro-4'-piperidino)propyl>-10,11-dihydro-5H-dibenzazepine (120167-35-3,120181-35-3,89419-40-9)

Guidance literature:

With triethylamine; In chloroform; for 5h; Heating;

DOI:10.1248/cpb.41.1074

upstream raw materials:

3-chloro-5-(3-methanesulfonyloxypropyl)-10,11-dihydro-5H-dibenzazepine