methyl 5-acetamido-4,7,8,9-tetra-O-acetyl-3,5-dideoxy-2-O-salicyoyl-D-galacto-2-nonulopyranoside

Base Information

• Chemical Name: methyl 5-acetamido-4,7,8,9-tetra-O-acetyl-3,5-dideoxy-2-O-salicyoyl-D-galacto-2-nonulopyranoside
• CAS No.: 82703-92-2
• Molecular Formula: C₂₇H₃₃NO₁₅
• Molecular Weight: 611.557
• Mol file: 82703-92-2.mol

Synonyms:methyl 5-acetamido-4,7,8,9-tetra-O-acetyl-3,5-dideoxy-2-O-salicyoyl-D-galacto-2-nonulopyranoside

Chemical Property of methyl 5-acetamido-4,7,8,9-tetra-O-acetyl-3,5-dideoxy-2-O-salicyoyl-D-galacto-2-nonulopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of methyl 5-acetamido-4,7,8,9-tetra-O-acetyl-3,5-dideoxy-2-O-salicyoyl-D-galacto-2-nonulopyranoside

There total 3 articles about methyl 5-acetamido-4,7,8,9-tetra-O-acetyl-3,5-dideoxy-2-O-salicyoyl-D-galacto-2-nonulopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

benzyl 2,3,4-tri-O-benzyl-β-D-galactopyranoside (35017-04-0) + N-acetyl-4,7,8,9-tetra-O-acetyl-2-chloro-2-deoxyneuraminic acid methyl ester (67670-69-3) → methyl-2,3-didehydro-4,7,8,9-tetra-O-acetyl-N-acetylneuraminate (73960-72-2) + Benzyl-2,3,4-tri-O-benzyl-6-O-(methyl-5-acetamido-4,7,8,9-tetra-O-acetyl-3,5-didesoxy-D-glycero-α-D-galacto-2-nonulopyranosylonat)-β-D-galactopyranosid (82703-91-1) + methyl 5-acetamido-4,7,8,9-tetra-O-acetyl-3,5-dideoxy-2-O-salicyoyl-D-galacto-2-nonulopyranoside (82703-92-2) + (2S,4S,5R,6R)-5-Acetylamino-4-hydroxy-2-((2R,3R,4S,5R)-3,4,5,6-tetrahydroxy-tetrahydro-pyran-2-ylmethoxy)-6-((1R,2R)-1,2,3-trihydroxy-propyl)-tetrahydro-pyran-2-carboxylic acid methyl ester (82703-90-0,82703-94-4,82703-96-6,82703-98-8)

Guidance literature:

With silver salicylate; In benzene; for 17h; Ambient temperature;

DOI:10.1016/S0008-6215(00)82584-7

Reference yield:

benzyl 2,3,4-tri-O-benzyl-β-D-galactopyranoside (35017-04-0) → methyl-2,3-didehydro-4,7,8,9-tetra-O-acetyl-N-acetylneuraminate (73960-72-2) + Benzyl-2,3,4-tri-O-benzyl-6-O-(methyl-5-acetamido-4,7,8,9-tetra-O-acetyl-3,5-didesoxy-D-glycero-α-D-galacto-2-nonulopyranosylonat)-β-D-galactopyranosid (82703-91-1) + methyl 5-acetamido-4,7,8,9-tetra-O-acetyl-3,5-dideoxy-2-O-salicyoyl-D-galacto-2-nonulopyranoside (82703-92-2) + (2S,4S,5R,6R)-5-Acetylamino-4-hydroxy-2-((2R,3R,4S,5R)-3,4,5,6-tetrahydroxy-tetrahydro-pyran-2-ylmethoxy)-6-((1R,2R)-1,2,3-trihydroxy-propyl)-tetrahydro-pyran-2-carboxylic acid methyl ester (82703-90-0,82703-94-4,82703-96-6,82703-98-8)

Guidance literature:

With silver salicylate; In benzene; for 17h; Ambient temperature;

DOI:10.1016/S0008-6215(00)82584-7

Reference yield:

N-acetyl-4,7,8,9-tetra-O-acetyl-2-chloro-2-deoxyneuraminic acid methyl ester (67670-69-3) + silver salicylate (528-93-8,14800-64-7) → methyl-2,3-didehydro-4,7,8,9-tetra-O-acetyl-N-acetylneuraminate (73960-72-2) + Benzyl-2,3,4-tri-O-benzyl-6-O-(methyl-5-acetamido-4,7,8,9-tetra-O-acetyl-3,5-didesoxy-D-glycero-α-D-galacto-2-nonulopyranosylonat)-β-D-galactopyranosid (82703-91-1) + methyl 5-acetamido-4,7,8,9-tetra-O-acetyl-3,5-dideoxy-2-O-salicyoyl-D-galacto-2-nonulopyranoside (82703-92-2) + (2S,4S,5R,6R)-5-Acetylamino-4-hydroxy-2-((2R,3R,4S,5R)-3,4,5,6-tetrahydroxy-tetrahydro-pyran-2-ylmethoxy)-6-((1R,2R)-1,2,3-trihydroxy-propyl)-tetrahydro-pyran-2-carboxylic acid methyl ester (82703-90-0,82703-94-4,82703-96-6,82703-98-8)

Guidance literature:

In benzene; for 17h; Ambient temperature;

DOI:10.1016/S0008-6215(00)82584-7

upstream raw materials:

benzyl 2,3,4-tri-O-benzyl-β-D-galactopyranoside

N-acetyl-4,7,8,9-tetra-O-acetyl-2-chloro-2-deoxyneuraminic acid methyl ester

silver salicylate