Technology Process of Thiazolo[5,4-h]isoquinolin-2(1H)-one, 6,7,8,9-tetrahydro- (9CI)
There total 3 articles about Thiazolo[5,4-h]isoquinolin-2(1H)-one, 6,7,8,9-tetrahydro- (9CI) which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydrogenchloride; sodium cyanoborohydride;
In
methanol;
for 24h;
Ambient temperature;
DOI:10.1021/jm00127a027
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 90 percent / DABCO / dimethylformamide / 24 h / Ambient temperature
2: 95 percent / SnCl2*2H2O, 12 N HCl, HOAc / 0.5 h / heating on steam bath
3: 38 percent / NaBH3CN, HCl-MeOH / methanol / 24 h / Ambient temperature
With
1,4-diaza-bicyclo[2.2.2]octane; hydrogenchloride; sodium cyanoborohydride; acetic acid; tin(ll) chloride;
In
methanol; N,N-dimethyl-formamide;
DOI:10.1021/jm00127a027
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 95 percent / SnCl2*2H2O, 12 N HCl, HOAc / 0.5 h / heating on steam bath
2: 38 percent / NaBH3CN, HCl-MeOH / methanol / 24 h / Ambient temperature
With
hydrogenchloride; sodium cyanoborohydride; acetic acid; tin(ll) chloride;
In
methanol;
DOI:10.1021/jm00127a027