3-(4-fluorostyryl)furan

Base Information

• Chemical Name: 3-(4-fluorostyryl)furan
• CAS No.: 128587-74-6
• Molecular Formula: C₁₂H₉FO
• Molecular Weight: 188.201

Synonyms:3-(4-fluorostyryl)furan

Chemical Property of 3-(4-fluorostyryl)furan

Chemical Property:

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Technology Process of 3-(4-fluorostyryl)furan

There total 1 articles about 3-(4-fluorostyryl)furan which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.0%

furan-3-carboxaldehyde (498-60-2) → 3-(4-fluorostyryl)furan (128587-74-6)

Guidance literature:

4-fluorobenzyl halide; With triphenyl phosphite; at 140 ℃; for 4h;

With sodium methylate; In tetrahydrofuran; for 0.5h; Cooling with ice;

furan-3-carboxaldehyde; In tetrahydrofuran; at 20 ℃;

DOI:10.1016/j.tetlet.2011.10.141

Reference yield: 35.0%

3-(4-fluorostyryl)furan (128587-74-6) → 2-Fluor-7-methylnaphthalin (29885-92-5)

Guidance literature:

With 1,8-diazabicyclo[5.4.0]undec-7-ene; In ethanol; benzene; for 6h; Inert atmosphere; UV-irradiation;

DOI:10.1016/j.tetlet.2011.10.141

upstream raw materials:

furan-3-carboxaldehyde

Downstream raw materials:

2-Fluor-7-methylnaphthalin

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