(2S,3S)-1-azido-2-hydroxy-3-<(tert-butyloxycarbonyl)amino>-4-cyclohexylbutane

Base Information

• Chemical Name: (2S,3S)-1-azido-2-hydroxy-3-<(tert-butyloxycarbonyl)amino>-4-cyclohexylbutane
• CAS No.: 108868-89-9
• Molecular Formula: C₁₅H₂₈N₄O₃
• Molecular Weight: 312.412

Synonyms:(2S,3S)-1-azido-2-hydroxy-3-<(tert-butyloxycarbonyl)amino>-4-cyclohexylbutane

Chemical Property of (2S,3S)-1-azido-2-hydroxy-3-<(tert-butyloxycarbonyl)amino>-4-cyclohexylbutane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2S,3S)-1-azido-2-hydroxy-3-<(tert-butyloxycarbonyl)amino>-4-cyclohexylbutane

There total 2 articles about (2S,3S)-1-azido-2-hydroxy-3-<(tert-butyloxycarbonyl)amino>-4-cyclohexylbutane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.0%

(2R,3S)-3-(t-butoxycarbonylamino)-4-cyclohexyl-1,2-epoxybutane (107202-61-9) → (2R,3S)-1-azido-2-hydroxy-3-<(tert-butyloxycarbonyl)amino>-4-cyclohexylbutane + (2S,3S)-1-azido-2-hydroxy-3-<(tert-butyloxycarbonyl)amino>-4-cyclohexylbutane (108868-89-9)

Guidance literature:

With sodium azide; ammonium chloride; In methanol; for 16h; Heating;

DOI:10.1021/jm00390a018

Reference yield:

→ (2S,3S)-1-azido-2-hydroxy-3-<(tert-butyloxycarbonyl)amino>-4-cyclohexylbutane (108868-89-9)

Guidance literature:

Reference yield: 87.0%

acetic acid (64-19-7,77671-22-8) + (2S,3S)-1-azido-2-hydroxy-3-<(tert-butyloxycarbonyl)amino>-4-cyclohexylbutane (108868-89-9) → (2S,3S)-1-amino-2-hydroxy-3-<(tert-butyloxycarbonyl)amino>-4-cyclohexylbutane acetic acid salt (108868-91-3)

Guidance literature:

With hydrogen; palladium on activated charcoal; for 9h;

DOI:10.1021/jm00390a018

upstream raw materials:

(2R,3S)-3-(t-butoxycarbonylamino)-4-cyclohexyl-1,2-epoxybutane

Downstream raw materials:

(2S,3S)-1-amino-2-hydroxy-3-<(tert-butyloxycarbonyl)amino>-4-cyclohexylbutane acetic acid salt

(2S,3S)-1-<<(3-methylbutyl)carbonyl>amino>-2-hydroxy-3-<(tert-butyloxycarbonyl)amino>-4-cyclohexylbutane

{(S)-1-[(S)-1-[(1S,2S)-1-Cyclohexylmethyl-2-hydroxy-3-(4-methyl-pentanoylamino)-propylcarbamoyl]-2-(1H-imidazol-4-yl)-ethylcarbamoyl]-2-phenyl-ethyl}-carbamic acid tert-butyl ester

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 108868-89-9 (2S,3S)-1-azido-2-hydroxy-3-<(tert-butyloxycarbonyl)amino>-4-cyclohexylbutane

Send

Send

Metric Ton KG G Pound L ML

Send

Send