2-{4-[1-(2-methylphenyl)-1-hydroxymethyl]phenyl}-4,4-dimethyl-2-oxazoline

Base Information

• Chemical Name: 2-{4-[1-(2-methylphenyl)-1-hydroxymethyl]phenyl}-4,4-dimethyl-2-oxazoline
• CAS No.: 175152-47-3
• Molecular Formula: C₁₉H₂₁NO₂
• Molecular Weight: 295.381

Synonyms:2-{4-[1-(2-methylphenyl)-1-hydroxymethyl]phenyl}-4,4-dimethyl-2-oxazoline

Chemical Property of 2-{4-[1-(2-methylphenyl)-1-hydroxymethyl]phenyl}-4,4-dimethyl-2-oxazoline

Chemical Property:

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Technology Process of 2-{4-[1-(2-methylphenyl)-1-hydroxymethyl]phenyl}-4,4-dimethyl-2-oxazoline

There total 2 articles about 2-{4-[1-(2-methylphenyl)-1-hydroxymethyl]phenyl}-4,4-dimethyl-2-oxazoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-(4-bromophenyl)-4,4-dimethyl-2-oxazoline (32664-14-5) → 2-{4-[1-(2-methylphenyl)-1-hydroxymethyl]phenyl}-4,4-dimethyl-2-oxazoline (175152-47-3)

Guidance literature:

With magnesium; In tetrahydrofuran;

Reference yield:

Br(1-)*C11H12MgNO(1+) + 2-methylphenyl aldehyde (529-20-4) → 2-{4-[1-(2-methylphenyl)-1-hydroxymethyl]phenyl}-4,4-dimethyl-2-oxazoline (175152-47-3)

Guidance literature:

In tetrahydrofuran; at 0 - 20 ℃; for 3h;

Reference yield:

2-{4-[1-(2-methylphenyl)-1-hydroxymethyl]phenyl}-4,4-dimethyl-2-oxazoline (175152-47-3) → 2-[4-(2-methylbenzoyl)phenyl]-4,4-dimethyl-2-oxazoline

Guidance literature:

With manganese dioxide; In dichloromethane;

upstream raw materials:

2-methylphenyl aldehyde

2-(4-bromophenyl)-4,4-dimethyl-2-oxazoline

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