FTI-2670

Base Information

• Chemical Name: FTI-2670
• CAS No.: 910910-62-2
• Molecular Formula: C₂₉H₄₀N₈O₄S
• Molecular Weight: 596.754

Synonyms:FTI-2670

Chemical Property of FTI-2670

Chemical Property:

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Technology Process of FTI-2670

There total 7 articles about FTI-2670 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

4-[(2-(N-tert-butoxycarbonylpiperidin-4-ylmethyl)-aminoethyl)-(3-methyl-3H-imidazol-4-ylmethyl)-amino]-benzonitrile (1186615-62-2) + 1-methyl-1H-imidazole-4-sulfonyl chloride (137049-00-4) → FTI-2670 (910910-62-2)

Guidance literature:

In acetonitrile; at 0 - 20 ℃; Inert atmosphere;

DOI:10.1016/j.chembiol.2009.01.014

Reference yield: 47.0%

→ FTI-2670 (910910-62-2)

Guidance literature:

Reference yield:

1-methyl-1H-imidazole-4-sulfonic acid {2-[(4-cyano-phenyl)-(3-methyl-3H-imidazol-4-ylmethyl)-amino]-ethyl}-amide (912482-46-3) + tert-butyl 4-(bromomethyl)piperidine-1-carboxylate (158407-04-6) → FTI-2670 (910910-62-2)

Guidance literature:

With caesium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 48h;

DOI:10.1021/jm060081v

upstream raw materials:

1-methyl-1H-imidazole-4-sulfonic acid {2-[(4-cyano-phenyl)-(3-methyl-3H-imidazol-4-ylmethyl)-amino]-ethyl}-amide

tert-butyl 4-(bromomethyl)piperidine-1-carboxylate

4-[(2-aminoethyl)-(3-methyl-3H-imidazol-4-ylmethyl)-amino]-benzonitrile

{2-[(4-cyanophenyl)amino]ethyl}carbamic acid tert-butyl ester

Downstream raw materials:

1-methyl-1H-imidazole-4-sulfonic acid {2-[(4-cyano-phenyl)-(3-methyl-3H-imidazol-4-ylmethyl)-amino]-ethyl}-piperidin-4-ylmethyl-amide

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