2-fluoro-N-prop-2-enylbenzamide

Base Information

Chemical Name:2-fluoro-N-prop-2-enylbenzamide
CAS No.:66896-69-3
Molecular Formula:C₁₀H₁₀FNO
Molecular Weight:179.194
Hs Code.:
DSSTox Substance ID:DTXSID501291895

Synonyms:N-Allyl-2-fluorobenzamide;66896-69-3;2-fluoro-N-prop-2-enylbenzamide;starbld0031873;DTXSID501291895;AKOS002958427;Benzamide, 2-fluoro-N-2-propen-1-yl-;2-FLUORO-N-(PROP-2-EN-1-YL)BENZAMIDE;F1911-3839

Suppliers and Price of 2-fluoro-N-prop-2-enylbenzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 2-fluoro-N-prop-2-enylbenzamide

Chemical Property:

XLogP3:2.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:179.074642105
Heavy Atom Count:13
Complexity:193

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C=CCNC(=O)C1=CC=CC=C1F

Technology Process of 2-fluoro-N-prop-2-enylbenzamide

There total 3 articles about 2-fluoro-N-prop-2-enylbenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 107-11-9,30551-89-4
1-amino-2-propene

: 445-29-4
o-fluoro-benzoic acid

: 66896-69-3
N-allyl-2-fluorobenzamide

Guidance literature:: With 1,1'-carbonyldiimidazole; In tetrahydrofuran; at 60 ℃; Inert atmosphere;
DOI:10.1021/acs.orglett.8b03170

Reference yield: 93.0%

: 107-11-9,30551-89-4
1-amino-2-propene

: 393-52-2
2-Fluorobenzoyl chloride

: 66896-69-3
N-allyl-2-fluorobenzamide

Guidance literature:: In toluene; at 20 ℃; for 12h;
DOI:10.1002/chem.200700477

Reference yield:

: 445-29-4
o-fluoro-benzoic acid

: 66896-69-3
N-allyl-2-fluorobenzamide

Guidance literature:: Multi-step reaction with 2 steps

1: N,N-dimethyl-formamide; oxalyl dichloride / dichloromethane / 6 h / 20 °C

2: triethylamine / dichloromethane / 3 h / 20 °C

With oxalyl dichloride; triethylamine; N,N-dimethyl-formamide; In dichloromethane;
DOI:10.1021/acs.orglett.6b02784