Technology Process of 2-Carbamyl-9-[beta-d-ribofuranosyl]hypoxanthine
There total 5 articles about 2-Carbamyl-9-[beta-d-ribofuranosyl]hypoxanthine which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 37 percent / n-pentyl nitrite / acetonitrile / 12 h / Heating
2: 1) NaOMe 2) NH4Cl / 1) methanol, 1h; 2) methanol, 1 h
3: 74 percent / KHSO5 / 12 h / 0 °C / acetate buffer, pH = 4.2
4: 40 percent / dimethylformamide / 15 h / 0 °C
5: 34 percent / NaOH, H2O2 (30percent) / ethanol / 1 h
With
sodium hydroxide; potassium peroxomonosulfate; n-Amyl nitrite; dihydrogen peroxide; sodium methylate; ammonium chloride;
In
ethanol; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1016/S0040-4020(01)86068-3
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 1) NaOMe 2) NH4Cl / 1) methanol, 1h; 2) methanol, 1 h
2: 74 percent / KHSO5 / 12 h / 0 °C / acetate buffer, pH = 4.2
3: 40 percent / dimethylformamide / 15 h / 0 °C
4: 34 percent / NaOH, H2O2 (30percent) / ethanol / 1 h
With
sodium hydroxide; potassium peroxomonosulfate; dihydrogen peroxide; sodium methylate; ammonium chloride;
In
ethanol; N,N-dimethyl-formamide;
DOI:10.1016/S0040-4020(01)86068-3
