methyl 3-[(4-tert-butylbenzoyl)amino]-4-[(4-methoxybenzoyl)amino]benzoate

Base Information

• Chemical Name: methyl 3-[(4-tert-butylbenzoyl)amino]-4-[(4-methoxybenzoyl)amino]benzoate
• CAS No.: 219492-47-4
• Molecular Formula: C₂₇H₂₈N₂O₅
• Molecular Weight: 460.53

Synonyms:methyl 3-[(4-tert-butylbenzoyl)amino]-4-[(4-methoxybenzoyl)amino]benzoate

Chemical Property of methyl 3-[(4-tert-butylbenzoyl)amino]-4-[(4-methoxybenzoyl)amino]benzoate

Chemical Property:

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Technology Process of methyl 3-[(4-tert-butylbenzoyl)amino]-4-[(4-methoxybenzoyl)amino]benzoate

There total 4 articles about methyl 3-[(4-tert-butylbenzoyl)amino]-4-[(4-methoxybenzoyl)amino]benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methyl 3,4-diaminobenzoate dihydrochloride → methyl 3-[(4-tert-butylbenzoyl)amino]-4-[(4-methoxybenzoyl)amino]benzoate (219492-47-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 44 percent / pyridine / acetonitrile

2: Et₃N / acetonitrile

With pyridine; triethylamine; In acetonitrile; 1: Acylation / 2: Acylation;

DOI:10.1021/jm990326m

Reference yield:

p-tert-butyl benzoyl chloride (1710-98-1) → methyl 3-[(4-tert-butylbenzoyl)amino]-4-[(4-methoxybenzoyl)amino]benzoate (219492-47-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 44 percent / pyridine / acetonitrile

2: Et₃N / acetonitrile

With pyridine; triethylamine; In acetonitrile; 1: Acylation / 2: Acylation;

DOI:10.1021/jm990326m

Reference yield:

p-tert-butyl benzoyl chloride (1710-98-1) + N2-(4-t-Butylbenzoyl)-4-methoxycarbonyl-1,2-benzenediamine (104224-96-6) → methyl 3-[(4-tert-butylbenzoyl)amino]-4-[(4-methoxybenzoyl)amino]benzoate (219492-47-4)

Guidance literature:

With triethylamine; In acetonitrile;

DOI:10.1021/jm990326m

upstream raw materials:

p-tert-butyl benzoyl chloride

N₂-(4-t-Butylbenzoyl)-4-methoxycarbonyl-1,2-benzenediamine

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