1-[2-[4-[3-[4-[3-(1-pyrrolidinyl)-1-propynyl]benzyl]benzo[b]thiophen-2-yl]phenoxy]ethyl]-pyrrolidine

Base Information

• Chemical Name: 1-[2-[4-[3-[4-[3-(1-pyrrolidinyl)-1-propynyl]benzyl]benzo[b]thiophen-2-yl]phenoxy]ethyl]-pyrrolidine
• CAS No.: 193963-06-3
• Molecular Formula: C₃₄H₃₆N₂OS
• Molecular Weight: 520.739
• Mol file: 193963-06-3.mol

Synonyms:1-[2-[4-[3-[4-[3-(1-pyrrolidinyl)-1-propynyl]benzyl]benzo[b]thiophen-2-yl]phenoxy]ethyl]-pyrrolidine

Chemical Property of 1-[2-[4-[3-[4-[3-(1-pyrrolidinyl)-1-propynyl]benzyl]benzo[b]thiophen-2-yl]phenoxy]ethyl]-pyrrolidine

Chemical Property:

Purity/Quality:

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MSDS Files:

Useful:

Technology Process of 1-[2-[4-[3-[4-[3-(1-pyrrolidinyl)-1-propynyl]benzyl]benzo[b]thiophen-2-yl]phenoxy]ethyl]-pyrrolidine

There total 1 articles about 1-[2-[4-[3-[4-[3-(1-pyrrolidinyl)-1-propynyl]benzyl]benzo[b]thiophen-2-yl]phenoxy]ethyl]-pyrrolidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

{2-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-benzo[b]thiophen-3-yl}-[4-(3-pyrrolidin-1-yl-prop-1-ynyl)-phenyl]-methanol → 1-[2-[4-[3-[4-[3-(1-pyrrolidinyl)-1-propynyl]benzyl]benzo[b]thiophen-2-yl]phenoxy]ethyl]-pyrrolidine (193963-06-3)

Guidance literature:

With triethylsilane; trifluoroacetic acid; Yield given;

DOI:10.1016/S0960-894X(98)00746-X

Reference yield: 61.0%

1-[2-[4-[3-[4-[3-(1-pyrrolidinyl)-1-propynyl]benzyl]benzo[b]thiophen-2-yl]phenoxy]ethyl]-pyrrolidine (193963-06-3) → C34H38N2OS

Guidance literature:

With diisobutylaluminium hydride; at 40 ℃;

DOI:10.1016/S0960-894X(98)00746-X

Reference yield: 44.0%

1-[2-[4-[3-[4-[3-(1-pyrrolidinyl)-1-propynyl]benzyl]benzo[b]thiophen-2-yl]phenoxy]ethyl]-pyrrolidine (193963-06-3) → C34H38N2OS

Guidance literature:

With hydrogen; Lindlar's catalyst;

DOI:10.1016/S0960-894X(98)00746-X