4-[Hydroxy-(10-oxo-10H-9-oxa-10λ⁵-phospha-phenanthren-10-yl)-methyl]-benzonitrile

Base Information

• Chemical Name: 4-[Hydroxy-(10-oxo-10H-9-oxa-10λ⁵-phospha-phenanthren-10-yl)-methyl]-benzonitrile
• CAS No.: 130444-55-2
• Molecular Formula: C₂₀H₁₄NO₃P
• Molecular Weight: 347.31

Synonyms:4-[Hydroxy-(10-oxo-10H-9-oxa-10λ⁵-phospha-phenanthren-10-yl)-methyl]-benzonitrile

Chemical Property of 4-[Hydroxy-(10-oxo-10H-9-oxa-10λ⁵-phospha-phenanthren-10-yl)-methyl]-benzonitrile

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-[Hydroxy-(10-oxo-10H-9-oxa-10λ⁵-phospha-phenanthren-10-yl)-methyl]-benzonitrile

There total 3 articles about 4-[Hydroxy-(10-oxo-10H-9-oxa-10λ⁵-phospha-phenanthren-10-yl)-methyl]-benzonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

2-(2-hydroxyphenyl)-phenylphosphonous acid (35948-24-4) + 4-cyanobenzaldehyde (105-07-7) → 4-[Hydroxy-(10-oxo-10H-9-oxa-10λ5-phospha-phenanthren-10-yl)-methyl]-benzonitrile (130444-55-2)

Guidance literature:

In acetonitrile; at 80 ℃; for 3h;

Reference yield:

6-Chloro-6H-dibenz<1,2>oxaphosphorin (32186-92-8) → 4-[Hydroxy-(10-oxo-10H-9-oxa-10λ5-phospha-phenanthren-10-yl)-methyl]-benzonitrile (130444-55-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 94 percent / water / methanol / 1 h / Heating

2: 98 percent / acetonitrile / 3 h / 80 °C

With water; In methanol; acetonitrile;

Reference yield:

2-Phenylphenol (90-43-7,287950-96-3) → 4-[Hydroxy-(10-oxo-10H-9-oxa-10λ5-phospha-phenanthren-10-yl)-methyl]-benzonitrile (130444-55-2)

Guidance literature:

Multi-step reaction with 3 steps

1: 1) PCl₃ 2) ZnCl₂ / 1) a) 0.5h, 50 deg C b) 2.5h, 140 deg C 2) 5h, 140 to 210 deg C

2: 94 percent / water / methanol / 1 h / Heating

3: 98 percent / acetonitrile / 3 h / 80 °C

With water; zinc(II) chloride; phosphorus trichloride; In methanol; acetonitrile;

upstream raw materials:

2-(2-hydroxyphenyl)-phenylphosphonous acid

4-cyanobenzaldehyde

6-Chloro-6H-dibenz<1,2>oxaphosphorin

2-Phenylphenol

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

✦Write with AI

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 130444-55-2 4-[Hydroxy-(10-oxo-10H-9-oxa-10λ⁵-phospha-phenanthren-10-yl)-methyl]-benzonitrile

Send

Send

Metric Ton KG G Pound L ML

Send

Send