(3R,4S)-4-(2,5-difluorophenyl)-1-{5-[1-(3-isobutyl-[1,2,4]oxadiazol-5-yl)piperidin-4-ylmethoxy]pyrimidin-2-yl}pyrrolidin-3-ylamine hydrochloride

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Chemical Name:(3R,4S)-4-(2,5-difluorophenyl)-1-{5-[1-(3-isobutyl-[1,2,4]oxadiazol-5-yl)piperidin-4-ylmethoxy]pyrimidin-2-yl}pyrrolidin-3-ylamine hydrochloride
CAS No.:1351339-29-1
Molecular Formula:C₂₆H₃₃F₂N₇O₂*ClH
Molecular Weight:550.051
Hs Code.:

Synonyms:(3R,4S)-4-(2,5-difluorophenyl)-1-{5-[1-(3-isobutyl-[1,2,4]oxadiazol-5-yl)piperidin-4-ylmethoxy]pyrimidin-2-yl}pyrrolidin-3-ylamine hydrochloride

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Chemical Property of (3R,4S)-4-(2,5-difluorophenyl)-1-{5-[1-(3-isobutyl-[1,2,4]oxadiazol-5-yl)piperidin-4-ylmethoxy]pyrimidin-2-yl}pyrrolidin-3-ylamine hydrochloride

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Technology Process of (3R,4S)-4-(2,5-difluorophenyl)-1-{5-[1-(3-isobutyl-[1,2,4]oxadiazol-5-yl)piperidin-4-ylmethoxy]pyrimidin-2-yl}pyrrolidin-3-ylamine hydrochloride

There total 1 articles about (3R,4S)-4-(2,5-difluorophenyl)-1-{5-[1-(3-isobutyl-[1,2,4]oxadiazol-5-yl)piperidin-4-ylmethoxy]pyrimidin-2-yl}pyrrolidin-3-ylamine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

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: 1351342-54-5
[(3R,4S)-1-[5-(1-cyanopiperidin-4-ylmethoxy)pyrimidin-2-yl]-4-(2,5-difluorophenyl)pyrrolidin-3-yl]carbamic acid tert-butyl ester

: N'-hydroxy-3-methylbutanimidamide

: 1351339-29-1
(3R,4S)-4-(2,5-difluorophenyl)-1-{5-[1-(3-isobutyl-[1,2,4]oxadiazol-5-yl)piperidin-4-ylmethoxy]pyrimidin-2-yl}pyrrolidin-3-ylamine hydrochloride

Guidance literature:: [(3R,4S)-1-[5-(1-cyanopiperidin-4-ylmethoxy)pyrimidin-2-yl]-4-(2,5-difluorophenyl)pyrrolidin-3-yl]carbamic acid tert-butyl ester; N'-hydroxy-3-methylbutanimidamide; With zinc(II) chloride; In diethyl ether; ethanol; at 20 ℃; for 1.5h;

With hydrogenchloride; In diethyl ether; ethanol; at 20 - 100 ℃; for 2h; microwave irradiation;

With ammonium hydroxide; In methanol; diethyl ether; ethanol;