4,5-Dihydro-2-<(2-aminophenyl)methylamino>-4-oxo-3-furancarboxylic acid ethyl ester

Base Information

Chemical Name:4,5-Dihydro-2-<(2-aminophenyl)methylamino>-4-oxo-3-furancarboxylic acid ethyl ester
CAS No.:152645-44-8
Molecular Formula:C₁₄H₁₆N₂O₄
Molecular Weight:276.292
Hs Code.:

Synonyms:4,5-Dihydro-2-<(2-aminophenyl)methylamino>-4-oxo-3-furancarboxylic acid ethyl ester

Suppliers and Price of 4,5-Dihydro-2-<(2-aminophenyl)methylamino>-4-oxo-3-furancarboxylic acid ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 4,5-Dihydro-2-<(2-aminophenyl)methylamino>-4-oxo-3-furancarboxylic acid ethyl ester

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4,5-Dihydro-2-<(2-aminophenyl)methylamino>-4-oxo-3-furancarboxylic acid ethyl ester

There total 3 articles about 4,5-Dihydro-2-<(2-aminophenyl)methylamino>-4-oxo-3-furancarboxylic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.0%

: 152645-39-1
4,5-Dihydro-2-<(2-nitrophenyl)methylamino>-4-oxo-3-furancarboxylic acid ethyl ester

: 152645-44-8
4,5-Dihydro-2-<(2-aminophenyl)methylamino>-4-oxo-3-furancarboxylic acid ethyl ester

Guidance literature:: With cyclohexene; palladium on activated charcoal; In ethanol; Heating;
DOI:10.1021/jo00074a059

Reference yield:

: 3320-86-3
2-nitrophenyl isocyanate

: 152645-44-8
4,5-Dihydro-2-<(2-aminophenyl)methylamino>-4-oxo-3-furancarboxylic acid ethyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 82 percent / Et₃N / CH₂Cl₂ / Ambient temperature

2: 86 percent / K₂CO₃ / dimethylformamide / 0.25 h / 60 - 70 °C

3: 59 percent / cyclohexene / 10percent Pd/C / ethanol / Heating

With potassium carbonate; triethylamine; cyclohexene; palladium on activated charcoal; In ethanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jo00074a059

Reference yield:

: 152645-34-6
4,5-Dihydro-2-<(2-nitrophenyl)amino>-4-oxo-3-furancarboxylic acid ethyl ester

: 152645-44-8
4,5-Dihydro-2-<(2-aminophenyl)methylamino>-4-oxo-3-furancarboxylic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 86 percent / K₂CO₃ / dimethylformamide / 0.25 h / 60 - 70 °C

2: 59 percent / cyclohexene / 10percent Pd/C / ethanol / Heating

With potassium carbonate; cyclohexene; palladium on activated charcoal; In ethanol; N,N-dimethyl-formamide;
DOI:10.1021/jo00074a059