Tert-butyl {(S)-1-methyl-2-oxo-2-[(S)-pyrrolidin-3-ylamino]ethyl}carbamate

Base Information

Chemical Name:Tert-butyl {(S)-1-methyl-2-oxo-2-[(S)-pyrrolidin-3-ylamino]ethyl}carbamate
CAS No.:122536-66-7
Molecular Formula:C₁₂H₂₃N₃O₃
Molecular Weight:257.333
Hs Code.:
DSSTox Substance ID:DTXSID10561637,DTXSID401126146
Mol file:122536-66-7.mol

Synonyms:122536-66-7;TERT-BUTYL {(S)-1-METHYL-2-OXO-2-[(S)-PYRROLIDIN-3-YLAMINO]ETHYL}CARBAMATE;tert-butyl N-[1-oxo-1-(pyrrolidin-3-ylamino)propan-2-yl]carbamate;LUQCQTCJUWASKJ-UHFFFAOYSA-N;SCHEMBL8121031;DTXSID10561637;DTXSID401126146;122536-97-4;tert-Butyl {1-oxo-1-[(pyrrolidin-3-yl)amino]propan-2-yl}carbamate;[1-Methyl-2-oxo-2-[(3-pyrrolidinyl)amino]ethyl]-carbamic acid 1,1-dimethylethyl ester;Carbamic acid, [1-methyl-2-oxo-2-(3-pyrrolidinylamino)ethyl]-, 1,1-dimethylethyl ester

Suppliers and Price of Tert-butyl {(S)-1-methyl-2-oxo-2-[(S)-pyrrolidin-3-ylamino]ethyl}carbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of Tert-butyl {(S)-1-methyl-2-oxo-2-[(S)-pyrrolidin-3-ylamino]ethyl}carbamate

Chemical Property:

PSA：86.44000
LogP:1.75120
XLogP3:0.4
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:257.17394160
Heavy Atom Count:18
Complexity:312

Purity/Quality:: 99% ，98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C(=O)NC1CCNC1)NC(=O)OC(C)(C)C

Technology Process of Tert-butyl {(S)-1-methyl-2-oxo-2-[(S)-pyrrolidin-3-ylamino]ethyl}carbamate

There total 9 articles about Tert-butyl {(S)-1-methyl-2-oxo-2-[(S)-pyrrolidin-3-ylamino]ethyl}carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 140412-80-2
*,R^*)>-3-<<2-<<(1,1-dimethylethoxy)carbonyl>amino>-1-oxopropyl>amino>-1-pyrrolidinecarboxylic acid phenylmethyl ester

: 122536-66-7
*,R^*)>-<1-methyl-2-oxo-2-(3-pyrrolidinylamino)ethyl>carbamic acid 1,1-dimethylethyl ester

Guidance literature:: With hydrogen; palladium on activated charcoal; In methanol; at 24.5 - 25.5 ℃; for 3h; under 2518.5 - 2668.5 Torr;
DOI:10.1021/jm00088a011

Reference yield:

: 140412-80-2
3-((R)-2-tert-Butoxycarbonylamino-propionylamino)-pyrrolidine-1-carboxylic acid benzyl ester

: 122536-66-7,122536-97-4,122537-11-5,140412-67-5,140412-68-6
[(R)-1-(Pyrrolidin-3-ylcarbamoyl)-ethyl]-carbamic acid tert-butyl ester

Guidance literature:: With hydrogen; palladium on activated charcoal; In methanol; at 24.5 - 25.5 ℃; for 3h; under 2518.5 - 2668.5 Torr;
DOI:10.1021/jm00088a011

Reference yield:

: 140412-80-2
3-((S)-2-tert-Butoxycarbonylamino-propionylamino)-pyrrolidine-1-carboxylic acid benzyl ester

: 122536-66-7,122536-97-4,122537-11-5,140412-67-5,140412-68-6
[(S)-1-(Pyrrolidin-3-ylcarbamoyl)-ethyl]-carbamic acid tert-butyl ester

Guidance literature:: With hydrogen; palladium on activated charcoal; In methanol; at 24.5 - 25.5 ℃; for 3h; under 2518.5 - 2668.5 Torr;
DOI:10.1021/jm00088a011