RA-X methyl ester

Base Information

Chemical Name:RA-X methyl ester
CAS No.:140679-95-4
Molecular Formula:C₄₄H₅₄N₆O₁₁
Molecular Weight:842.946
Hs Code.:

Synonyms:RA-X methyl ester

Suppliers and Price of RA-X methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of RA-X methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of RA-X methyl ester

There total 1 articles about RA-X methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 186581-53-3,908094-01-9,334-88-3
diazomethane

: 140679-94-3
C₄₃H₅₂N₆O₁₁

: 140679-95-4
RA-X methyl ester

Guidance literature:: In diethyl ether; Ambient temperature;

Reference yield: 74.0%

: 140679-95-4
RA-X methyl ester

: 153445-49-9
<2-(δ-hydroxynorvaline)>-RA-VII

Guidance literature:: With lithium borohydride; In tetrahydrofuran; for 12h; Ambient temperature;
DOI:10.1248/cpb.41.1402

Reference yield:

: 140679-95-4
RA-X methyl ester

: <2-pipecolic acid>-RA-VII

Guidance literature:: Multi-step reaction with 9 steps

1: 74 percent / LiBH₄ / tetrahydrofuran / 12 h / Ambient temperature

2: 96 percent / DMAP, Et₃N / CH₂Cl₂ / 1 h / -78 °C

3: 1.) o-nitrophenylselenecyanate, NaBH₄, 2.) 35percent aq. H₂O₂ / 1.) EtOH, RT, 3 h, 2.) THF-EtOH, RT, 12 h

4: 76 percent / OsO₄, NaIO₄ / dioxane; H₂O / 18 h / Ambient temperature

5: 72 percent / NaH, 18-crown-6 / tetrahydrofuran / 12 h / Ambient temperature

6: H₂ / 10percent Pd/C / dioxane / 24 h / Ambient temperature

7: LiBH₄ / tetrahydrofuran / 24 h / Ambient temperature

8: 58.1 g / DMAP, Et₃N / CH₂Cl₂ / 1 h / -78 °C

9: n-Bu₄NBr, 50percent NaOH / CH₂Cl₂ / 1 h / Ambient temperature

With dmap; sodium hydroxide; sodium tetrahydroborate; sodium periodate; osmium(VIII) oxide; lithium borohydride; ortho-nitrophenyl selenocyanate; 18-crown-6 ether; tetrabutylammomium bromide; hydrogen; dihydrogen peroxide; sodium hydride; triethylamine; palladium on activated charcoal; In tetrahydrofuran; 1,4-dioxane; dichloromethane; water;
DOI:10.1248/cpb.41.1402